63762-07-2

Basic information

• Product Name: 1-Pyrrolidinecarboxylic acid, 2-(chloroacetyl)-, phenylmethyl ester, (S)-
• CAS NO: 63762-07-2
• Molecular Formula: C14H16ClNO3
• Molecular Weight: 281.739
• Mol File: 63762-07-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Pyrrolidinecarboxylic acid, 2-(chloroacetyl)-, phenylmethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxylic acid, 2-(chloroacetyl)-, phenylmethyl ester, (S)-(63762-07-2)
• EPA Substance Registry System: 1-Pyrrolidinecarboxylic acid, 2-(chloroacetyl)-, phenylmethyl ester, (S)-(63762-07-2)

Safety Data

• Hazardous Substances Data: 63762-07-2(Hazardous Substances Data)

Upstream product

• 1148-11-4 N-carbobenzyloxyproline 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 
• 56633-71-7 2-(S)-(2-diazo-1-oxoethyl)pyrrolidine-1-carboxylic acid benzyl ester 
• 89705-40-8 rac-N-benzyloxycarbonyl-proline acid chloride 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 888319-22-0 2-[4-(4-fluoro-phenyl)-4-oxo-3-pyridin-4-yl-butyryl]-pyrrolidine-1-carboxylic acid benzyl ester 
• 111491-98-6 (2S)-2-Acetyl-N-(benzyloxycarbonyl)pyrrolidine 
• 1427161-79-2 C₂₆H₂₈N₄O₂S 
• 111492-03-6 Z-L-Glp-L-Leu-L-ProCH₃ 
• 888319-19-5 5'-(4-fluoro-phenyl)-4'-pyridin-4-yl-2,3,4,5-tetrahydro-1'H-[2,2']bipyrrolyl-1-carboxylic acid benzyl ester 
• 888319-14-0 5'-(4-fluoro-phenyl)-4'-pyridin-4-yl-2,3,4,5-tetrahydro-1H,1'H-[2,2']bipyrrolyl 

Relevant articles and documents

Synthesis and anti-Candida activity of novel 2-hydrazino-1,3-thiazole derivatives

Eighteen new hydrazino-1,3-thiazole derivatives were evaluated against 8 strains of multi-resistant Candida spp. Introduction of an indolyl moiety linked to the hydrazone function enhanced the in vitro anti-Candida activity, with an activity spectrum towards Candida albicans strains. Introduction of a (S)-2-aminoethyl chain on the thiazole nucleus largely enhanced the in vitro antifungal activity, with a selectivity oriented towards non-C. albicans species.

α-Amino Ketones - A Contribution to the Synthesis of Optically Active Derivatives of Amino Acids and Peptides

The synthesis of N-Z-protected methyl ketones from amino acids via the chloromethyl ketones and dehalogenation of the latter with zinc in glacial acetic acid is described.Deprotection of the methyl ketones results in the formation of hydrohalogenides of the α-aminoalkyl methyl ketones further converted to N-acylated peptide ketones as analogs of peptide hormones or as competitively acting substrate analogs of proteolytic enzymes.Aminoacetone is conveniently prepared as well as methyl-pyrrolidyl ketone and methyl-piperidyl ketone.