63770-48-9

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.

Explanation

The compound is derived from a benzisoxazole, which is a heterocyclic compound containing both benzene and isoxazole rings, with a nitro group attached to the 5th position.

Explanation

A heterocyclic compound is a cyclic compound containing atoms of different elements, in this case, carbon, nitrogen, and oxygen.

Explanation

The nitro group (-NO2) is a functional group consisting of a nitrogen atom bonded to two oxygen atoms, which is attached to the 5th position of the benzisoxazole ring.

Explanation

The compound is known for its potential applications in the pharmaceutical industry due to its various biological activities and pharmacological properties.

Explanation

1,2-Benzisoxazole, 3-methyl-5-nitrois used as a building block for the synthesis of various drug molecules and agrochemicals, contributing to the development of new compounds with desired properties.

Explanation

The compound is used as a research tool in organic synthesis and medicinal chemistry due to its unique structural features and reactivity, which can be exploited to develop new synthetic methods and drug candidates.

Explanation

The compound has been found to exhibit various biological activities, which contribute to its potential use in the development of pharmaceuticals and agrochemicals.

Explanation

The compound's pharmacological properties, such as its ability to interact with biological targets, make it a valuable candidate for further research and development in the pharmaceutical industry.

Chemical Structure

Nitro-substituted benzisoxazole derivative

Heterocyclic Compound

Contains both benzene and isoxazole rings

Nitro Group

Attached to the 5th position

Potential Applications

Pharmaceutical industry

Building Block

Synthesis of drug molecules and agrochemicals

Research Tool

Organic synthesis and medicinal chemistry

Biological Activities

Exhibits various biological activities

Pharmacological Properties

Displays pharmacological properties

Upstream product

• 1450-76-6 1-(2-hydroxy-5-nitrophenyl)ethanone 
• 1247949-39-8 2-(1-iminoethyl)-4-nitrophenol 
• 54595-48-1 (Z)-1-(2-bromo-5-nitrophenyl)ethanone oxime 
• 23082-50-0 2'-chloro-5'-nitroacetophenone 

Downstream Products

• 851768-35-9 3-methylbenzo[d]isoxazol-5-amine 

Relevant academic research and scientific papers

PYRAZOLOPYRROLIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Pyrazolopyrrolidine Derivatives and their Use in the Treatment of Disease

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

A divergent and selective synthesis of isomeric benzoxazoles from a single N-Cl imine

A divergent and regioselective synthesis of either 3-substituted benzisoxazoles or 2-substituted benzoxazoles from readily accessible ortho-hydroxyaryl N-H ketimines is described. The reaction proceeds in two distinct pathways through a common N-Cl imine intermediate: (a) N-O bond formation to form benzisoxazole under anhydrous conditions and (b) NaOCl mediated Beckmann-type rearrangement to form benzoxazole, respectively. The reaction path also depends on the electronic nature of the aromatic ring, with the electron-rich aromatic rings favoring the rearrangement and the electron-deficient rings favoring the N-O bond formation. A Beckmann-type rearrangement mechanism via net [1,2]-aryl migration for the formation of 2-substituted benzoxazole is proposed.

Copper-catalyzed cyclization of Z-oximes into 3-methyl-1,2-benzisoxazoles

A practical and effective room temperature copper-catalyzed cyclization of Z-oximes is developed. 3-Methyl-1,2-benzisoxazoles are obtained in 58-79% yields. Also, the Z-selective synthesis of o-bromo acetophenone oximes is presented for the first time.

PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS FROM CARBAMATE COMPOUNDS

An improved process for the preparation of 6-(perfluoroalkyl)uracil compounds having structural formula (I) from carbamate compounds having structural formula (II).

Processes and intermediate compounds for the preparation of 2-(N,N-disubstituted) amino-4-(perfluoroalkyl)-1, 3- oxazin-6-one and 6-(perfluoroalkyl) uracil compounds

An improved process and intermediate compounds for the preparation of 2-(N,N-disubstituted)amino-4-(perfluoroalkyl)-1,3-oxazin-6-one compounds having the structural formula I and an improved process for the preparation of 6-(perfluoroalkyl)uracil compound

3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents

There are provided 3-(1,2-benzisothiazol- and isoxazol-5-yl)-2,4(1H,3H)-pyrimidinedione or thione compounds of formula I and 3-(1,2-benzisothiazol- and isoxazol-5-yl)-4(3H)-pyrimidinone or thione compounds of formula II Further provided are compositions and methods comprising those compounds for the control of undesirable plant species.