54595-48-1

Upstream product

• 551-93-9 2-aminoacetophenone 
• 1215858-76-6 2-bromo-1-(2-bromo-5-nitrophenyl)ethanone oxime 
• 2142-69-0 2-bromophenyl methyl ketone 
• 65130-31-6 1-(2′-bromo-5′-nitrophenyl)ethan-1-one 

Downstream Products

• 54582-26-2 α-6-bromo-3-nitro-acetophenone oxime 
• 63770-48-9 3-methyl-5-nitrobenzo[d]isoxazole 

Relevant academic research and scientific papers

Copper-catalyzed cyclization of Z-oximes into 3-methyl-1,2-benzisoxazoles

A practical and effective room temperature copper-catalyzed cyclization of Z-oximes is developed. 3-Methyl-1,2-benzisoxazoles are obtained in 58-79% yields. Also, the Z-selective synthesis of o-bromo acetophenone oximes is presented for the first time.