637740-15-9

Upstream product

• 637739-92-5 2-(allyl-benzoyl-amino)-acrylic acid ethyl ester 
• 637739-93-6 2-benzoyl-2-azabicyclo[2.1.1]hexane-1-carboxylic acid ethyl ester 
• 637739-94-7 (2-benzyl-2-azabicyclo[2.1.1]hex-1-yl)methanol 
• 637739-99-2 (2-azabicyclo[2.1.1]hex-1-yl)-methanol 
• 501-53-1 benzyl chloroformate 
• 637739-98-1 1-hydroxymethyl-2-azabicyclo[2.1.1]hexane-2-carboxylic acid benzyl ester 

Downstream Products

• 1124345-61-4 benzyl 1-(4-carbamoyl-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.1.1]hexane-2-carboxylate 

Relevant academic research and scientific papers

NOVEL INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)

A compound having the structure set forth in Formula (I): wherein the variables Y, R1, R2, R3, R4 and R5 are as defined herein. Compounds described herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of such compounds and pharmaceutical compositions to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity

Modification of 1-Substituents in the 2-Azabicyclo[2.1.1]hexane Ring System; Approaches to Potential Nicotinic Acetylcholine Receptor Ligands from 2,4-Methanoproline Derivatives

Successful nucleophilic substitution at a methylene attached to the bridgehead (1-) position of the 2-azabicyclo[2.1.1]hexane ring system opens the way to construction of novel derivatives having a wider range of functional groups attached to the 1-positi