63780-71-2Relevant academic research and scientific papers
HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS
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Page/Page column 84, (2008/06/13)
The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
Generation of doubly trifluoromethylsubstituted carbocations: Synthesis of α,α-Bis(trifluoromethyl)benzylamines
Nesi, Marcella,Brasca, Maria Gabriella,Longo, Antonio,Moretti, Walter,Panzeri, Achille
, p. 4881 - 4884 (2007/10/03)
α,α-Bis(trifluoromethylbenzyl)triflates offer a convenient access to the corresponding amines through S(N)1 type reactions.
