63783-79-9Relevant academic research and scientific papers
A highly efficient asymmetric synthesis of optically active α,β-epoxyaldehydes from α,β-unsaturated acids
Terashima, Shiro,Hayashi, Masaji,Koga, Kenji
, p. 2733 - 2736 (2007/10/02)
The bromolactones(3) prepared from α,β-unsaturated acids(1) were converted to optically active α,β-epoxyaldehydes(2(R),3(S)-6)(84-98% ee) by successive epoxide formation and reductive cleavage of the proline moiety. The overall process constitutes a highly efficient asymmetric synthesis of 2(R),3(S)-6 from 1.
