63785-87-5

Basic information

• Product Name: 5-BroMo-1-ethylpyridin-2(1h)-one
• Synonyms: 5-BroMo-1-ethylpyridin-2(1h)-one;5-Bromo-1-ethyl-1H-pyridin-2-one
• CAS NO: 63785-87-5
• Molecular Formula: C₇H₈BrNO
• Molecular Weight: 202.04852
• Mol File: 63785-87-5.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-BroMo-1-ethylpyridin-2(1h)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BroMo-1-ethylpyridin-2(1h)-one(63785-87-5)
• EPA Substance Registry System: 5-BroMo-1-ethylpyridin-2(1h)-one(63785-87-5)

Safety Data

• Hazardous Substances Data: 63785-87-5(Hazardous Substances Data)

Usage

General Description

5-Bromo-1-ethylpyridin-2(1H)-one, also known as BGP-15, is a chemical compound with potential therapeutic applications. It is a pyridine derivative with a bromine and an ethyl group attached to the pyridine ring. BGP-15 has been studied for its antioxidant, anti-inflammatory, and anti-diabetic properties. It has shown promise in preclinical studies for its ability to protect against cellular stress and reduce inflammation, making it a potential candidate for the treatment of various diseases and conditions. Research on BGP-15 continues to explore its pharmacological properties and potential therapeutic uses.

Upstream product

• 13337-79-6 1-ethyl-2-pyridone 
• 504-29-0 2-aminopyridine 
• 1072-97-5 5-bromo-2-pyridylamine 
• 81590-30-9 5-bromo-2-hydroxypyrimidine hydrobromide 
• 75-03-6 ethyl iodide 
• 74-96-4 ethyl bromide 
• 13466-38-1 5-bromopyridin-2(1H)-one 
• 13466-38-1 5-bromopyridin-2-ol 

Downstream Products

• 1349734-00-4 1-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2(1H)-one 
• 1352152-30-7 (S)-tert-butyl 1-(1-amino-3-(4-(1-ethyl-6-oxo-1,6-dihydropyridin-3-yl)phenyl)-1-oxopropan-2-ylcarbamoyl)cyclohexylcarbamate 
• 1352152-29-4 (S)-1-amino-N-(1-cyano-2-(4-(1-ethyl-6-oxo-1,6-dihydropyridin-3-yl)phenyl)ethyl)cyclohexanecarboxamide 
• 1352152-31-8 (S)-tert-butyl 1-(1-cyano-2-(4-(1-ethyl-6-oxo-1,6-dihydropyridin-3-yl)phenyl)ethylcarbamoyl)cyclohexylcarbamate 
• 77555-17-0 5-cyclohexyl-N-ethyl-2-pyridone 
• 77555-18-1 N,N-diethyl-6,6-dioxo-3,3-bipyridyl 

Relevant articles and documents

TRIAZOLO-PYRIMIDINE COMPOUNDS AND USES THEREOF

The present disclosure relates to novel triazolo-pyrimidine compounds targeting adenosine receptors (especially A1 and A2, particularly A2a). The present disclosure also relates to pharmaceutical compositions comprising one or more of the compounds as an active ingredient, and use of the compounds in the treatment of adenosine receptor (AR) associated diseases, for example cancer such as NSCLC, RCC, prostate cancer, and breast cancer.

Substituted thiazole derivative and application thereof

The invention provides a compound represented by a general formula (I), or a stereoisomer, pharmaceutically acceptable salt, solvate, hydrate, chemically protective form or prodrug thereof. The compound has an effect of inhibiting adenosine receptor 2a (A2a), and can be used as an antagonist of the adenosine receptor 2a (A2A) for treating tumors.

DI-SUBSTITUTED PYRAZOLE COMPOUNDS FOR THE TREATMENT OF DISEASES

Provided herein are compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds and compositions in treating a condition, disease, or disorder associated with abnormal activation of the SREBP pathway, including metabolic disorders such as obesity, cancer, cardiovascular disease, and nonalcoholic fatty liver disease (NAFLD) wherein the compound is according to Formula (I).