6382-93-0

Basic information

• Product Name: Z-D-ARG-OH
• Synonyms: Z-D-ARGININE extrapure;Cbz-D-Arginine;N-Carbobenzoxy-D-arginine;Nα-Carbobenzyloxy-D-arginine ,98%;N-a-Cbz-D-arginine - (Z-D-Arg-OH);Nalpha-Cbz-D-arginine Z-D-Arg-OH;N^a-Benzyloxycarbonyl-D-arginine, 98%;Nα-Carbobenzyloxy-D-arginine
• CAS NO: 6382-93-0
• Molecular Formula: C₁₄H₂₀N₄O₄
• Molecular Weight: 308.33
• Product Categories: Z-Amino Acids and Derivatives;Amino Acids;Amino Acids (N-Protected);Biochemistry;Cbz-Amino Acids;Z-Amino acid series
• Mol File: 6382-93-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 168-171 °C
• Boiling Point: 448.73°C (rough estimate)
• Appearance: white powder
• Density: 1.1765 (rough estimate)
• Refractive Index: 8 ° (C=5.5, HCl)
• Storage Temp.: -20°C
• CAS DataBase Reference: Z-D-ARG-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-D-ARG-OH(6382-93-0)
• EPA Substance Registry System: Z-D-ARG-OH(6382-93-0)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 6382-93-0(Hazardous Substances Data)

Usage

Chemical Properties

white powder

Uses

Nα-Cbz-D-arginine is an N-Cbz-protected form of D-Arginine (A769515). D-Arginine is an unnatural isomer of L-Arginine (A769505), and is used to inhibit glutamate-induced nitric oxide production in rats. Derivatives of D-Arginine are used for pharmaceutical purposes, one example is 1-Deamino-8-D-arginine vasopressin, which is used to treat various bleeding disorders.

InChI:InChI=1/C14H20N4O4/c15-13(16)17-8-4-7-11(12(19)20)18-14(21)22-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,18,21)(H,19,20)(H4,15,16,17)/t11-/m1/s1

Upstream product

• 157-06-2 D-arginine 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 632323-92-3 (R)-5-Guanidino-2-[(Z)-3-(4-hydroxy-phenyl)-acryloylamino]-pentanoic acid [2-(2-amino-ethoxy)-ethyl]-amide 
• 632323-84-3 N-(2-(tert-butoxycarbonylamino)ethoxyethyl) N_α-benzyloxycarbonyl-D-arginine amide 
• 74-79-3 L-arginine 
• 100-51-6 benzyl alcohol 
• 632323-91-2 N-(2-(tert-butoxycarbonylamino)ethoxyethyl) N_α-cis-p-coumaroyl-D-arginine amide 

Relevant articles and documents

Fluorescence studies on nyctinasty using fluorescence labeled cis-p-coumaroylagmatine, a leaf-opening substance of Albizzia plants: Existence of genus-specific receptor for leaf-movement factor

We developed fluorescent probes (1 and 2) based on the structure of cis-p-coumaroylagmatine (3), a leaf-opening substance of Albizzia julibrissin Durazz. These probes were effective for the leaf-opening of A. julibrissin, and specifically bind to the moto