638212-22-3

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 
• 5997-56-8 4-methyl-N-(oxiran-2-ylmethyl)benzenesulfonamide 
• 638212-21-2 6-[N-(2,3-epoxypropyl)-N-tosyl]amino-5-nitro-1,3-dimethyluracil 

Downstream Products

• 638212-24-5 toluene-4-sulfonic acid 1,3-dimethyl-2,4-dioxo-9-(toluene-4-sulfonyl)-2,3,4,5,6,7,8,9-octahydro-1H-pyrimido[4,5-b][1,4]diazepin-7-yl ester 
• 638212-23-4 7-hydroxy-1,3-dimethyl-9-(toluene-4-sulfonyl)-1,5,6,7,8,9-hexahydro-pyrimido[4,5-b][1,4]diazepine-2,4-dione 

Relevant academic research and scientific papers

Syhthesis of the tetrahydropteridine-2,4-dione having a substituted methyl group at 6-position

Lewis acid treatment of 5-amino-6-(N-2,3-epoxypropyl-N-tosyl)amino-1,3-dimethyluracil (3) gave the diazepine (4) fused to uracil ring, and the tosylate (5) from 4 underwent ring transformation to provide tetrahydropteridinediones (7 and 8) depending on th