63837-30-9

Usage

Uses

Used in Pesticide Industry:
1,2-Propanediol, 3-(4-phenoxyphenoxy)is used as an intermediate in the synthesis of Diofenolan, a Juvenile hormone agonist for insect pest control. 1,2-Propanediol, 3-(4-phenoxyphenoxy)plays a crucial role in the development of effective and environmentally friendly pest management solutions.

Upstream product

• 84267-54-9 2-[(4-phenoxyphenoxy)methyl]oxirane 
• 25345-76-0 1-phenoxy-4-allyloxybenzene 
• 831-82-3 4-Phenoxyphenol 
• 584-08-7 potassium carbonate 
• 96-24-2 3-monochloro-1,2-propanediol 

Downstream Products

• 145033-17-6 2R,4S-2-ethyl-4-[(4-phenoxyphenoxy)methyl]dioxolan 
• 823221-77-8 1-methoxymethoxy-3-(4-phenoxy-phenoxy)propan-2-ol 

Relevant academic research and scientific papers

Cerium ammonium nitrate: A new catalyst for regioselective protection of glycols

The regioselective introduction of a methoxymethyl (MOM) group on different type of glycols via an orthoester intermediate was investigated. The novelty presented in this study is the use of ceric ammonium nitrate instead of the previously employed camphorsulfonic acid as catalyst. The monoprotection reaction was revealed to be highly selective when the glycol moiety was in the presence of an ether functionality. Graphical abstract

Design, synthesis, and biological evaluation of new growth inhibitors of Trypanosoma cruzi (epimastigotes)

As a continuation of our project aimed at the search for new chemotherapeutic agents against Chagas' disease, several drugs structurally related to the insect growth regulator Fenoxycarb and the naturally occurring juvenfie hormone of insects were designed, synthesized, and evaluated as antiproliferative agents against the parasite responsible of this disease. Isoprenoid derivatives (compounds 33, 34, 36, and 37) were potent growth inhibitors of Trypanosoma cruzi epimastigotes. In addition, taking into account the high activity observed for compound 30 and the inhibitory action of related compounds, the allyl ether moiety bonded at the polar extreme of these inhibitors proved to be a promising group for the design of new drugs.

Process for the manufacture of phenoxyphenoxyalkyl derivatives

The invention relates to a process for the manufacture of a compound of the formula in which eitherR1 is hydrogen and R2 is hydrogen orO-R1 and O-R2 taken together are the group of the formula a compound of the