63839-90-7

Upstream product

• 100-52-7 benzaldehyde 
• 95-13-6 1-indene 

Downstream Products

• 66374-17-2 trans-2-phenylspiro 

Relevant academic research and scientific papers

Synthesis of Functionalized (η5-Indenyl)rhodium(III) Complexes and Their Application to C?H Bond Functionalization

It has been established that reductive complexation of functionalized benzofulvenes, which are readily prepared from commercially available indene and 2-methylindene, with RhCl3 in ethanol affords the corresponding indenyl–rhodium(III) dichlorides bearing substituents at the 1- (H or CO2Et), 2- (H or Me), and 3- [CH2Ph or CH2(2-MeOC6H4)] positions. The indenyl–rhodium(III) complexes bearing one ethoxycarbonyl group showed higher thermal stability and regioselectivity than our previously reported CpERhIII complex toward the oxidative [3+2] annulation of acetanilides with internal alkynes.

A Rapid and Highly Efficient Method for the Synthesis of Benzofulvenes via CsOH-Catalyzed Condensation of Indene and Aldehydes

A fast condensation of indene with a wide range of aldehydes catalyzed by cesium hydroxide monohydrate (CsOH·H2O) for the synthesis of benzofulvenes with good to excellent yields was demonstrated. The condensation can be completed within a few minutes under room temperature and air atmosphere without the use of special ligands or phase-transfer catalysts. In addition, the ratio of indene to aldehydes played an important role in this reaction. The single condensation products 3 can be obtained as main products with a ratio of 1.2:1, whereas the double condensation products 4 can be obtained by changing the ratio to 1:2.2. This protocol provides an efficient, simple and general method for the synthesis of benzofulvenes 3 and double condensation products 4, which are important intermediates in the synthesis of numerous drugs and natural products.

Water-soluble calixarenes as new inverse phase-transfer catalysts. Their application to aldol-type condensation and Michael addition reactions in water

Aldol-type condensation and Michael addition reactions of activated methyl and methylene compounds in aqueous NaOH solution have been developed without the need for any added organic solvents. The water-soluble calix[n]arenes, which contain trimethylammon

Fullerene tectonics. Part 1. A programmed precursor to C60

Soluble polycyclic tectonic building blocks for C60 have been prepared by the cyclotrimerisation of aromatic ketones. Electron impact fragmentation pathways are described.

Condensation reactions in water of active methylene compounds with arylaldehydes. One-pot synthesis of flavonols

The condensation reactions of acetophenone, cyclohexanone, isophorone, phenylacetonitrile, p-nitrophenylacetonitrile, (phenylsulfonyl)acetonitrile and indene with benzaldehyde were studied in water heterogeneous phase in the presence and absence of anionic and cationic surfactants such as SLS, CTACl, (CTA)2SO4 and CTAOH. All the reactions occur with excellent yields. The cationic surfactants favour the reaction and the comparison with the corresponding tetrabutylammonium salts show that the micellar catalysis is effective mainly towards the dehydration reaction following that of condensation. Anionic surfactant SLS is inactive. 2'-hydroxychalcones were prepared in aqueous medium in good-excellent yields and the one-pot synthesis of 7- and 3',4'-substituted flavonols was achieved.

ACTIVATION DE LA LIAISON C-H FAIBLEMENT ACIDE PAR ADSORPTION SUR KF-Al2O3

Condesation of poorly acidic carbon compounds (pka 18-30) with benzaldehyde was achieved by adsorption without solvent on KF-Al2O3.KF-Al2O3 appears as a stronger base than KF.