63856-19-9Relevant academic research and scientific papers
Divergent synthesis of N-heterocycles by Pd-catalyzed controllable cyclization of vinylethylene carbonates
Yang, Yuwen,Yang, Weibo
, p. 12182 - 12185 (2018)
Here, we report a palladium-catalyzed controllable cyclization of vinyl ethylene carbonates that proceeds through formal migration [2+3] and [5+2] cycloadditions, respectively, under mild conditions. The transformation described here affords a series of synthetically versatile 5,7-membered N-heterocycles which are found in natural products and pharmaceuticals with biological and medicinal properties.
Divergent Synthesis of Aziridine and Imidazolidine Frameworks under Blue LED Irradiation
Cheng, Xiao,Cai, Bao-Gui,Mao, Hui,Lu, Juan,Li, Lei,Wang, Kun,Xuan, Jun
supporting information, p. 4109 - 4114 (2021/05/26)
We develop a visible light-promoted divergent cycloaddition of α-diazo esters with hexahydro-1,3,5-triazines, leading to a series of aziridine and imidazolidine frameworks in average good yield, by simply changing the reaction media used. It is noteworthy that the reaction occurs under sole visible light irradiation without the need for exogenous photoredox catalysts. More significantly, a reasonable reaction mechanism was proposed on the basis of the control experiments and density functional theory calculation results.
Process for the preparation of 1,3-disubstituted-2-azetidinones from triazines
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, (2008/06/13)
A process for preparing an azetidinone of the formula: STR1 which comprises reacting a C-unsubstituted methyleneamine of the formula: STR2 with R2 --CH2 COOH, its acid halide or anhydride, in the presence of boron trihalide and an organic base, wherein R1 is an organic residue bearing a carboxy group or its derivative and R2 is azido, substituted amino, halogen, acyloxy, alkoxy, aryloxy or aralkoxy.
2-Azetidinone compounds and processes for preparation thereof
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, (2008/06/13)
This invention relates to new 2-azetidinone compounds, which have antimicrobial activities, and to processes for the preparation thereof, and more particularly, this invention provides new 2-azetidinone compounds, especially ones having various substituted carboxyalkyl radicals at the first position and having various groups at the fourth position of the azetidinone nucleus, which have antimicrobial activities against various pathogenic microorganisms and are useful as antibiotics in treatment for microbial infections in mammal including human being and animals.
