6394-69-0

Upstream product

• 513-38-2 Isobutyl iodide 
• 4831-18-9 N-phenacyl-p-toluidine 
• 1075-06-5 2,2-dihydroxy-1-phenyl-ethanone 
• 106-49-0 p-toluidine 
• 98-86-2 acetophenone 
• 1074-12-0 phenylglyoxal hydrate 

Downstream Products

• 106824-13-9 1-((2R,3R)-2-Benzoyl-4-oxo-1-p-tolyl-azetidin-3-yl)-pyrrole-2,5-dione 
• 158229-62-0 4-Cyano-5-oxo-3-phenyl-1-p-tolyl-2,5-dihydro-1H-pyrrole-2-carboxylic acid cyclohexylamide 
• 17685-52-8 triiron dodecarbonyl 
• 1256650-07-3 C₁₇H₁₅NO₂S 
• 1610600-17-3 (3,8-dimethyl-1,4-diphenyl-1,5,9,10-tetrahydropyrazolo[4',3':6,7]azepino[5,4,3-cd]indol-9-yl)(phenyl)methanone 
• 107209-64-3 (2-methylphenanthridin-6-yl)(phenyl)methanone 
• 107209-49-4 (8-Methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)-phenyl-methanone 
• 107209-61-0 (2-Methyl-5,6,6a,7,8,10a-hexahydro-phenanthridin-6-yl)-phenyl-methanone 
• 17539-90-1 N-(p-tolyl)-1-phenyl-2-aminoethanol 
• 106824-10-6 2-((2R,3R)-2-Benzoyl-4-oxo-1-p-tolyl-azetidin-3-yl)-isoindole-1,3-dione 

Relevant academic research and scientific papers

Highly Efficient Copper-Catalyzed Dehydrogenative Cross-Coupling of Azoles with α-Amino Carbonyl Compounds

A novel and highly efficient dehydrogenative cross-coupling- reaction between α-amino carbonyl compounds and azoles by copper catalysis using di- tert -butyl peroxide (DTBP) as an oxidant is described-. A diverse range of azoles undergo the dehydrogenative imidoylation smoothly with various α-amino carbonyl compounds for the exclusive formation of the corresponding N -imidoyl azoles in high yields under air. The synthetic method has the advantages of good functional-group tolerance, wide substrate scope, excellent yields, and simple operation-, thus providing a convenient and practical protocol for the synthesis of functionalized azoles.

Reductive Alkylation of α-Keto Imines Catalyzed by PTSA/FeCl3: Synthesis of Indoles and 2,3′-Biindoles

A simple and efficient method for the synthesis of highly functionalized indoles and biindoles was developed. In the reaction protocol, three components were used in one pot and products were obtained in high yield in an easy workup procedure. The reactio

Antifungal activities of ketoazomethines of phenyl glyoxal and p-substituted anilines

A new series of ketoazomethines were synthesized by condensation of phenyl glyoxal (prepared by partial oxidation of acetophenone) with various p-substituted anilines viz. p-Cl, p-Br, p-NO2, p-(C2H 5)2N and p-CH

Synthesis and antifungal activity of 2-Ketophenyl-3 substituted aryl-1-thiazolidin-4-ones

A new series of 2-ketophenyl-3-substituted aryl-1- thiazolidin-4- ones were synthesized by cyclocondensation of ketoazomethines and thioglycolic acid. Ketoazomethines were synthesized by condensation of phenyl glyoxal (prepared by partial oxidation of ace

Studies on isocyanides and related compounds: A novel synthesis of pyrroles via Ugi reaction

A series of N-substituted 1,3-diaryl-4-cyano-2,5-dihydro-5-oxopyrrole-2-carboxamides 9 is obtained by reacting arylglyoxal anils 6 with isocyanides 3 and cyanoacetic acid (2). Compounds 9 react quickly with diazomethane to give N-substituted 1,3-diaryl-4-

The Reaction of Phenylglyoxal with Primary Aliphatic and Aromatic Amines. Synthesis of Phenylglyoxal Monoimines and some Derivatives.

Condensation of phenylglyoxal with primary aliphatic amines yields the related keto-aldimines.When primary aromatic amines are used, aldimines, amino-hydroxy-ketones, diamino-ketones, and alkoxy-amino-ketones are obtained depending upon the nature of the amine and the experimental conditions.Alternatively the monoimines can be obtained by dehydration of C-hydroxyphenacylarylamines and by demethanolation of C-methoxyphenacylarylamines both on treatment with Pd/C catalyst.Reduction of phenylglyoxal monoimines with sodium borohydride yielded H-substituted 1-phenyl-2-aminoethanols and 1,3-dipolar cycloaddition of the imines with p-chlorobenzonitrile oxide afforded 4-substituted 5-benzoyl-3-(p-chlorophenyl)-4,5-dihydro-1,2,4-oxadiazoles.

Oxidation of Phenacylanilines with Lead Tetraacetate

Oxidation of phenacylanilines (Ia-d) with lead tetraacetate in dry benzene gives the corresponding anils (IIa-d) and N-acetyl derivatives (IIIa-d) of phenacylanilines.