639819-17-3

Basic information

• Product Name: tert-butyl 5-nitrobenzothiophene-2-carboxylate
• Synonyms: tert-butyl 5-nitro-1-benzothiophene-2-carboxylate; tert-Butyl-5-nitro-1-benzothiophen-2-carboxylat
• CAS NO: 639819-17-3
• Molecular Formula: C₁₃H₁₃NO₄S
• Molecular Weight: 279.31
• Mol File: 639819-17-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 409.1°C at 760 mmHg
• Flash Point: 201.2°C
• Density: 1.315g/cm³
• Vapor Pressure: 6.66E-07mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: tert-butyl 5-nitrobenzothiophene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 5-nitrobenzothiophene-2-carboxylate(639819-17-3)
• EPA Substance Registry System: tert-butyl 5-nitrobenzothiophene-2-carboxylate(639819-17-3)

Safety Data

• Hazardous Substances Data: 639819-17-3(Hazardous Substances Data)

Upstream product

• 6345-55-7 5-nitrobenzo[b]thiophene-2-carboxylic acid 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 639819-18-4 t-butyl 5-aminobenzo[b]thiophene-2-carboxylate 

Relevant articles and documents

Synthesis and growth inhibition activity of α-bromoacrylic heterocyclic and benzoheterocyclic derivatives of distamycin A modified on the amidino moiety

The design, synthesis and in vitro activities of novel α-bromoacryloyl pyrazole, imidazole and benzoheterocyclic derivatives of distamycin A, in which the amidino moiety has been replaced by moieties of different physico-chemical features are described, and the structure-activity relationships are discussed. In spite of the relevance of these modifications on the distamycin frame, these derivatives showed significant growth inhibitory activity against mouse leukemia L1210 cells. Therefore, the presence of the amidino moiety, and in general of a basic moiety, is not an absolute requirement for biological activity of α-bromoacrylic derivatives of distamycin.