639858-45-0

Basic information

• Product Name: 5-AMino-2,4-difluorobenzoic acid, 98%
• Synonyms: 5-AMino-2,4-difluorobenzoic acid, 98%
• CAS NO: 639858-45-0
• Molecular Formula: C₇H₅F₂NO₂
• Molecular Weight: 173.1169064
• Mol File: 639858-45-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 325.2±42.0 °C(Predicted)
• Appearance: /
• Density: 1.536±0.06 g/cm3(Predicted)
• PKA: 3.42±0.10(Predicted)
• CAS DataBase Reference: 5-AMino-2,4-difluorobenzoic acid, 98%(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMino-2,4-difluorobenzoic acid, 98%(639858-45-0)
• EPA Substance Registry System: 5-AMino-2,4-difluorobenzoic acid, 98%(639858-45-0)

Safety Data

• Hazardous Substances Data: 639858-45-0(Hazardous Substances Data)

Usage

Uses

5-Amino-2,4-difluorobenzoic Acid is used in the preparation of dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 inhibitors.

Upstream product

• 153775-33-8 2,4-difluoro-5-nitro-benzoic acid 

Downstream Products

• 658085-51-9 5-amino-2,4-difluoro-N-methoxybenzamide 
• 125568-73-2 2,4-difluoro-5-aminobenzoic acid methyl ester 
• 639858-44-9 5-amino-2,4-difluoro-N-methylbenzamide 

Relevant articles and documents

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The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-ca

Heterocyclic inhibitors of kinases

The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.