63995-75-5

Usage

Uses

Used in Catalyst Industry:
DIPHENYLPHOSPHINOBENZENE-3-SULFONIC ACID SODIUM SALT is used as a water-soluble phosphine ligand for the formation of water-soluble catalysts. Its water-soluble nature allows for improved catalytic efficiency and reduced environmental impact in chemical reactions.
Used in Pharmaceutical Industry:
DIPHENYLPHOSPHINOBENZENE-3-SULFONIC ACID SODIUM SALT is used as a component in the development of anti-cancer gold compounds. These compounds have shown potential in targeting and treating various types of cancer, making them a valuable addition to the field of oncology.

InChI:InChI=1/C18H15O3PS.Na/c19-23(20,21)18-13-7-12-17(14-18)22(15-8-3-1-4-9-15)16-10-5-2-6-11-16;/h1-14H,(H,19,20,21);/q;+1/p-1

Upstream product

• 603-35-0 triphenylphosphine 
• 112998-09-1 sodium 3-(diphenylphosphinyl)benzenesulfonate 

Downstream Products

• 130946-98-4 (2-formyl-1-phenylethenyl)diphenyl(3-sulfophenyl)phosphonium chloride, sodium salt 
• 130946-98-4 (2-formyl-1-phenylethenyl)diphenyl(3-sulfophenyl)phosphonium chloride, sodium salt 
• 112998-09-1 sodium 3-(diphenylphosphinyl)benzenesulfonate 
• 122570-62-1 (2-carboxyethenyl)diphenyl(3-sulfophenyl)phosphonium inner salt, sodium salt 
• 130946-96-2 (2-carbopentoxyethenyl)diphenyl(3-sulfophenyl)phosphonium chloride, sodium salt 
• 130946-96-2 (2-carbopentoxyethenyl)diphenyl(3-sulfophenyl)phosphonium chloride, sodium salt 
• 80780-93-4 (Z)-4-(Diphenyl-phosphinoyl)-but-3-en-2-one 
• 122866-02-8 C₁₅H₁₄⁽²⁾HO₃P 
• 122865-78-5 C₂₁H₁₈O₅PS^(1-)*Na⁽¹⁺⁾ 
• 122865-80-9 C₂₁H₁₇⁽²⁾HO₅PS^(1-)*Na⁽¹⁺⁾ 

Relevant academic research and scientific papers

A practical synthesis of a disulfonated phosphine and its application to biphasic catalysis

A convenient synthesis of TPPDS (disodium P-phenyl-3,3'-phosphinediyl- bis(benzenesulfonate)) from triphenylphosphine is described. This represents a quick and reliable way to prepare a water-soluble phosphine with essentially no phosphine oxide formation. (C) 2000 Elsevier Science Ltd.

A clean and efficient conversion of aldehydes into the corresponding nitriles using ionic supported triphenylphosphine and CBr4

An ionic supported triphenylphosphine and carbon tetrabromide system has been applied to the clean and efficient conversion of various aromatic and aliphatic aldehydes to the corresponding nitriles.

Catalysts for Suzuki polycondensation: Ionic and "quasi-ionic" amphipathic palladium complexes with self-phase-transfer features

Poly(9,9-dioctylfluorene) (PFO) with Mn values above 100 000 g mol-1 in a toluene/water system and Mn values up to 600 000 g mol-1 in a THF/water system has been obtained by improved Suzuki polycondensation using a new kind of amphipathic palladium catalyst with self-phase-transfer features, which could overcome the disadvantage caused by the immiscible biphasic mixture and accelerate the transmetalation step (see figure). Copyright

High-yield synthesis and crystal structure determination of sodium triphenylphosphane monosulfonate (TPPMSNa)

A. simple, high-yield synthesis is described that leads to the sodium salt of monosulfonated triphenylphosphane (TPPMSNa) as a pure product in large quantities without complicated workup techniques. The single-crystal X-ray structure of TPPMSNa-2.5H2O is reported. The structure is built up by alternating layers of aquated sodium sulfonate units and hydrophobic triphenyl units. Thermogravimetric analyses show the loss of one molecule of water at 70 and. one at 105 °C. Thermal decomposition occurs at temperatures above 400 °C. The anhydrous ligand is hygroscopic. The preparation of the free acid TPPMSH starting from the sodium, salt is also reported. TPPMSH is an extremely hygroscopic solid that could not be isolated in the crystalline form.

ZWITTERIONIC PHOSPHONIUM SALTS

A zwitterionic phosphonium salt of Formula I: wherein n is 0 or 1; R is H or SO3-; R' is selected from the group consisting of C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, C3-C10 cycloalkyl, phenyl, substituted phenyl, benzyl and C1-C10 alkoxycarbonyl; R' is CX3 when n is O; and X is selected from the group consisting of F, Cl, Br and I. The zwitterionic phosphonium salts are useful reagents for the preparation of alkenes and acetals from the corresponding aldehyde.

Zwitterionic phosphonium sulfonates as easily phase-separable ion-tagged wittig reagents

(Chemical Equation Presented) Zwitterionic phosphonium sulfonates 3, conveniently derived from TPPMS (1), can be used as Wittig reagents in solution. The excess reagents and byproduct TPPMSO (6) can be easily separated from the product alkenes by simple precipitation with a less polar solvent. The alkenes thus obtained were often sufficiently pure without chromatographic purification. A one-pot protocol for the synthesis of α,β-unsaturated esters has been developed and appears to be convenient.

Facile synthesis of a monosulfonated triphenylphosphane (TPPMS) derived ligand having strong π-acceptor character

Two phenyl rings of triphenylphosphane have been modified by electron-withdrawing trifluoromethyl groups. A methoxy group has been introduced at the para-position of the third ring. Due to the activating effect of the methoxy group, the phosphane can be m

LITHIUM P-DIARYLPHOSPHINOBENZENESULFONATES, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF

Lithium p-diarylphosphinobenzenesulfonates represented by the general formula (I) wherein R1 and R2 are each optionally substituted aryl; a process for preparing the same; a group VIII metal complex comprising a group VIII metal compound and the above lithium p-diarylphosphinobenzenesulfonate coordinating thereto and a process for hydroformylation with the complex. Hydroformylation with the complex permits easy and industrially advantageous production of aldehydes.

Phosphonium salts and processes for production of and uses for the same, and phosphines deriving the same and processes for production of the phosphines

Phosphonium salts represented by the general formula (I) wherein R1and R2each represents a phenyl group which may be substituted by a lower alkyl group, R3represents a phenylene group which may be substituted by a lower al

Optimisation of palladium-based supported liquid-phase catalysts in the heck reaction

Heck reactions using sulphonated triphenylphosphine palladium complexes have been carried out using a supported liquid-phase catalysis system in a batch reactor. The catalyst complex is held in solution in a polar, hydrophilic film supported upon porous glass beads whilst reactants and products are restricted to a nonmiscible solvent phase. Several factors in the preparation of the supported catalyst were investigated with the aim of ensuring good assembly, distribution, and immobilisation of the catalyst complex across the surface of the beads. The thickness of the hydrophilic film upon the porous glass beads was varied. The hydrophilic nature of the ligand complex was studied using mono- and trisulphonated sodium and lithium salts of triphenylphosphine. The effects of level of catalyst loading and ligand/catalyst ratio upon leaching and activity were also examined. These factors have been examined to develop a better understanding of the catalysis occurring in supported liquid-phase systems.