80780-93-4Relevant academic research and scientific papers
Aza-Michael reaction as an efficient method for the synthesis of first representatives of β-azahetaryl-β-diphenylphosphorylalkanones
Galkina,Bodrin,Goryunov,Goryunova,Ambartsumyan,Vasil’eva,Protopopova,Saifutiarova,Uryupin,Brel,Kochetkov
, p. 1855 - 1858 (2016)
Aza-Michael reaction of (E)-4-(diphenylphosphoryl)but-3-en-2-one (1) with a number of mono-and bicyclic nitrogen heterocycles proceeds regioselectively in the absence of catalysts with the formation of corresponding β-azahetaryl β-diphenylphosphoryl keton
β-Diphenylphosphorylated alkanones and related compounds: Synthesis and structure
Goryunov,Bodrin,Goryunova,Nelyubina,Petrovskii,Strelkova,Peregudov,Matveeva,Pasechnik,Matveev,Nifant'Ev
, p. 780 - 791 (2014/01/23)
The reactions of diphenyl(diisopropyl)chlorophosphine with arylidene(heteroarylidene)-acetones and 3-benzylidenepentane-2,4-dione in the presence of acetic acid proceed at a high rate at room temperature to afford the corresponding β-diorganylphosphorylated alkanones and alkanediones in high yields. The reaction of diphenylchlorophosphine with 4-methoxybut-3-en-2-one and dibenzylideneacetone carried out under similar conditions at the equimolar reagent ratio can serve as a convenient method for the synthesis of unique β-diphenylphosphorylalkenones. The structures of compounds obtained were established by IR, Raman, and NMR spectroscopy and X-ray diffraction.
ORGANIC CHEMISTRY IN WATER (PART V) NUCLEOPHILIC ADDITION OF WATER-SOLUBLE PHOSPHINES ON ACTIVATED ALKYNES: AN EFFICIENT SYNTHESIS OF NEW VINYLPHOSPHONIUM SALTS AND OF SPECIFICALLY DEUTERATED OLEFINS.
Larpent, Chantal,Meignan, Gerard,Patin, Henri
, p. 6381 - 6398 (2007/10/02)
Triphenylphosphine m-trisulfonate 1 and triphenylphosphine m-monosulfonate 2 react in water with activated alkynes R-CC-A (A = CO2H, CO2R1, COR2, CHO) affording new vinylphosphonium salts or vinylphosphine oxides or alkenes depending on the pH of the aqueous solution and on the nature of the substituent R.The reactions of 1 or 2 with alkynes bearing an electron-acceptor substituent R give rise to the corresponding trans disubstituted olefins.Specifically mono or dideuterated alkenes are thus obtained in good yields by sequential use of H2O-D2O.When R = H or Alkyl, vinylphosphonium salts or vinylphosphine oxides are quantitatively produced respectively in acidic or in neutral solution.
Phosphinyl-Substituted Dienophiles: Their Synthesis and Directive Effects
Darling, Stephen D.,Brandes, Stephanie J.
, p. 1413 - 1416 (2007/10/02)
The unilateral directive influence of the carbonyl group in the Diels-Alder reaction can be negated by a diphenylphosphinyl group.The dienophile 4-(diphenylphosphinyl)-3-buten-2-one (4) was synthesized.Products isolated as a result of the addition of 4 to
