640-33-5 Usage
Uses
Used in Medical Applications:
(11alpha,15alpha)-11,15-dihydroxypregn-4-ene-3,20-dione is used as a medication for preventing miscarriage and treating certain hormone-related conditions such as endometriosis and certain types of cancer. It helps regulate hormone levels and supports the normal functioning of the reproductive system.
Used in Pharmaceutical Industry:
(11alpha,15alpha)-11,15-dihydroxypregn-4-ene-3,20-dione is used as an intermediate in the synthesis of other steroid hormones. It plays a key role in the production of various medications used to treat hormonal imbalances and other related conditions.
Used in Research and Laboratory Settings:
(11alpha,15alpha)-11,15-dihydroxypregn-4-ene-3,20-dione is used as a research compound to study hormone function and regulation. It helps scientists understand the complex mechanisms of hormone action and develop new treatments for hormone-related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 640-33-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,4 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 640-33:
(5*6)+(4*4)+(3*0)+(2*3)+(1*3)=55
55 % 10 = 5
So 640-33-5 is a valid CAS Registry Number.
640-33-5Relevant academic research and scientific papers
Microbial hydroxylation of hydroxyprogesterones and α-glucosidase inhibition activity of their metabolites
Choudhary, Muhammad Iqbal,Nasir, Muhammad,Khan, Shamsun N.,Atif, Muhammad,Ali, Rahat A.,Khalil, Syed M.,Atta-ur-Rahman
, p. 593 - 599 (2007/10/03)
Microbial transformation of 11α-hydroxyprogesterone (1) with Cunninghamella elegans, Gibberella fujikuroi, Fusarium lini, and Candida albicans yielded 11α,15α,16α-trihydroxypregn-4-ene-3,20-dione (3), 11α-hydroxy-5α-pregnane-3,20-dione (4), 6β,11α- dihydroxypregn-4-ene-3,20-dione(5), 11α-hydroxypregna-1,4-diene-3,20-dione (6), 11α,17β-dihydroxyandrost-4-en-3-one (7), and 11α,15α-dihydroxypregn-4-ene-3,20-dione (8). On the other hand, microbial transformation of 17α-hydroxyprogesterone (2) with Cunninghamella elegans and Fusarium Uni yielded 11α,17α- dihydroxypregn-4-ene-3,20-dione (9), and 17α-hydroxypregna-1,4-diene-3,20- dione (10). The structures of the metabolites 3-10 were deduced on the basis of spectroscopic methods. Compound 3 was identified as a new metabolite, which exhibited a promising inhibitory activity against the α-glucosidase enzyme.
