64001-70-3

Usage

Uses

Used in Medicinal Chemistry:
4-(1,3,4-OXADIAZOL-2-YL)PYRIDINE is used as a building block for the development of pharmaceuticals and agrochemicals due to its unique structure and properties that contribute to the synthesis of novel compounds with potential biological activities.
Used in Biological Imaging and Analytical Chemistry:
4-(1,3,4-OXADIAZOL-2-YL)PYRIDINE is used as a fluorescent probe in biological imaging and analytical chemistry applications, capitalizing on its potential to enhance imaging techniques and analytical processes in these fields.
Used in Chemistry, Biology, and Materials Science:
4-(1,3,4-OXADIAZOL-2-YL)PYRIDINE is employed across various applications in the fields of chemistry, biology, and materials science, owing to its promising properties and potential for the development of innovative products and technologies.

InChI:InChI=1/C7H5N3O/c1-3-8-4-2-6(1)7-10-9-5-11-7/h1-5H

Upstream product

• 54-85-3 isoniazid 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 122-51-0 orthoformic acid triethyl ester 
• 187964-68-7 N-(1H-1,2,3-benzotriazol-1-ylmethylene)-N-methylmethanaminium chloride 
• 15264-63-8 5-(pyridin-4-yl)-1,3,4-oxadiazol-2(3H)-thione 
• 5459-11-0 ethyl isonicotinoylhydrazonoformate 

Relevant academic research and scientific papers

Direct Annulation of Hydrazides to 1,3,4-Oxadiazoles via Oxidative C(CO)-C(Methyl) Bond Cleavage of Methyl Ketones

A new strategy for the synthesis of 1,3,4-oxadiazoles was established through direct annulation of hydrazides with methyl ketones. It was found that the use of K2CO3 as a base achieves an unexpected and highly efficient C-C bond clea

Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles

A novel one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles by condensation of acid hydrazide and triethyl orthoalkanates under microwave irradiations is reported. This green protocol was catalyzed efficiently by solid supported NafionNR50 and phosphorus pentasulfide in alumina (P4S10/Al2O3) with excellent yields.

HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

The application is directed to haloalkyl-substituted compounds of Formula (I), wherein R1, R1a, R2, R3, R4’ and E are as defined in the claims. The compounds are inhibitors of cysteine proteases, in p

AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceu

Novel compounds and compositions as cathepsin S inhibitors

The present invention relates to novel selective cathepsin S inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.

PEPTIDIC COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.