64002-51-3

Basic information

• Product Name: methanediol, 1-(2-ethoxyphenyl)-, diacetate
• Synonyms: (2-Ethoxyphenyl)methylene diacetate
• CAS NO: 64002-51-3
• Molecular Formula: C₁₃H₁₆O₅
• Molecular Weight: 252.2631
• Mol File: 64002-51-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 343.991°C at 760 mmHg
• Flash Point: 149.877°C
• Density: 1.147g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.499
• CAS DataBase Reference: methanediol, 1-(2-ethoxyphenyl)-, diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: methanediol, 1-(2-ethoxyphenyl)-, diacetate(64002-51-3)
• EPA Substance Registry System: methanediol, 1-(2-ethoxyphenyl)-, diacetate(64002-51-3)

Safety Data

• Hazardous Substances Data: 64002-51-3(Hazardous Substances Data)

Upstream product

• 613-69-4 2-ethoxylbenzaldehyde 
• 108-24-7 acetic anhydride 

Downstream Products

• 613-69-4 2-ethoxylbenzaldehyde 
• 64-19-7 acetic acid 

Relevant articles and documents

Microwave-assisted green synthesis of 1,1-diacetates (acylals) using selectfluor as an environmental-friendly catalyst under solvent-free conditions

An efficient and simple procedure has been developed for the acetylation of aldehyde by selectfluor [1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo[2,2,2]octane bis(tetrafluoroborate)] as a chemoselective and environmentally friendly catalyst under solvent-free conditions or microwave irradiation. The application of microwave irradiation improved the yields and reduced the reaction times. In this study, selective conversion of aldehydes was observed in the presence of ketones, and the deprotection of 1,1-diacetates has also been achieved using selectfluor in water as green solvent in reflux conditions. The methodology provides synergy of microwave irradiation which offers several advantages such the simple work-up procedure, short reaction time, excellent yields and environmentally benign procedure.

Chemoselective synthesis of 1,1-diacetates from aldehydes in the presence of Al(HSO4)3 under mild solvent-free conditions

A novel efficient procedure has been developed for the preparation of acylals in high yields by reaction of the corresponding aldehydes with acetic anhydride in the presence of Al(HSO4)3 as catalyst under mild (room temperature) solvent-free conditions.

Acetylation of aromatic ethers using acetic anhydride over solid acid catalysts in a solvent-free system. Scope of the reaction for substituted ethers

The acetylation of aryl ethers using acetic anhydride in the presence of zeolites under modest conditions in a solvent-free system gave the corresponding para-acetylated products in high yields. The zeolite can be recovered, regenerated and reused to give almost the same yields as that given when fresh zeolite is used.