64017-86-3

Basic information

• Product Name: Butanamide, N-(phenylmethyl)-4-[(phenylmethyl)amino]-
• CAS NO: 64017-86-3
• Molecular Formula: C18H22N2O
• Molecular Weight: 282.385
• Mol File: 64017-86-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Butanamide, N-(phenylmethyl)-4-[(phenylmethyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanamide, N-(phenylmethyl)-4-[(phenylmethyl)amino]-(64017-86-3)
• EPA Substance Registry System: Butanamide, N-(phenylmethyl)-4-[(phenylmethyl)amino]-(64017-86-3)

Safety Data

• Hazardous Substances Data: 64017-86-3(Hazardous Substances Data)

Upstream product

• 22813-61-2 N-benzyl-4-chlorobutanamide 
• 100-46-9 benzylamine 

Downstream Products

• 5291-77-0 1-benzyl-2-pyrrolidone 

Relevant articles and documents

Investigations into the mechanism of lactamization of lactones yielding in a novel route to biologically active tryptamine derivatives

The mechanism of lactamization of corresponding lactones was investigated by means of gas chromatography and synthesis of possible intermediates as references. Lactones react with amines via the amino acid with subsequent elimination of water to the corresponding lactams. In the first step, also hydroxyamides are in equilibrium with the lactones and amines, respectively, which are not able to form the amide though. This mechanism opens a new approach for the synthesis of Nβ-disubstituted tryptamines.