22813-61-2

Basic information

• Product Name: N-Benzyl-4-chlorobutyraMide, 97%
• Synonyms: N-Benzyl-4-chlorobutyraMide, 97%
• CAS NO: 22813-61-2
• Molecular Formula: C₁₁H₁₄ClNO
• Molecular Weight: 211.68796
• Mol File: 22813-61-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Benzyl-4-chlorobutyraMide, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: N-Benzyl-4-chlorobutyraMide, 97%(22813-61-2)
• EPA Substance Registry System: N-Benzyl-4-chlorobutyraMide, 97%(22813-61-2)

Safety Data

• Hazardous Substances Data: 22813-61-2(Hazardous Substances Data)

Upstream product

• 3153-36-4 4-chloro-butyric acid ethyl ester 
• 100-46-9 benzylamine 
• 19340-88-6 N-benzyl-4-hydroxybutanamide 
• 4635-59-0 4-Chlorobutanoyl chloride 

Downstream Products

• 950101-21-0 C₂₀H₁₉N₅OS 
• 181959-65-9 4-acetylthio-N-benzylbutyrylamide 
• 136408-34-9 (Z)-N-benzyl 5,6-dicarbomethoxy-5-hexenamide 
• 73963-33-4 1-Benzyl-5-(3-chloro-propyl)-1H-tetrazole 
• 136408-38-3 N-benzyl-4-iodobutanamide 
• 64017-86-3 N-benzyl-4-(benzylamino)butanamide 
• 5291-77-0 1-benzyl-2-pyrrolidone 

Relevant articles and documents

The efficient preparation of α, β, γ-lactam derivatives

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Trimethylaluminium mediated amide bond formation in a continuous flow microreactor as key to the synthesis of rimonabant and efaproxiral

A safe, functional-group-tolerant and high-throughput version of the trimethylaluminium mediated amide bond formation reaction has been developed in a microreactor system; rimonabant and efaproxiral were prepared to illustrate the utility of the method. The Royal Society of Chemistry.

Preparation and reactivity of chiral β-amino-alkylzinc iodides and related configurationally stable zinc organometallics

Several zinc organometallics bearing at the β-position a carbamate or an amido function with an acidic N-H group were prepared using the direct insertion of zinc dust into the corresponding alkyl iodides in THF or THF:DMSO mixtures. Most of the starting iodides were obtained from natural α-amino acids and the resulting zinc species afforded after transmetalation with CuCN.2LiCl and reaction with a selection of relatively reactive electrophiles a variety of polyfunctional 1,2-amino alcohol derivatives and carbamates in optically pure form. Several secondary β-amido alkyl iodides were converted to the corresponding chiral zinc reagents and trapped with electrophiles. The configurational stability of chiral secondary organozinc compounds and the stereochemical course of their reactions were examined.