64019-93-8 Usage
Uses
Used in Ophthalmology:
Dipivefrin hydrochloride is used as an anti-glaucoma agent for the treatment of open-angle glaucoma or ocular hypertension. It functions by reducing intraocular pressure, which helps to prevent optic nerve damage and slow the progression of glaucoma.
Used in Adrenergic Ophthalmic Treatments:
As an adrenergic ophthalmic agent, dipivefrin hydrochloride is utilized to stimulate the adrenergic receptors in the eye, leading to a decrease in the production of aqueous humor and an increase in uveoscleral outflow. This dual action contributes to the reduction of intraocular pressure, making it a valuable component in the management of glaucoma and ocular hypertension.
Brand Names:
Dipivefrin hydrochloride is available under various brand names, including Akpro (Akorn) and Propine (Allergan), which are used for the treatment of glaucoma and ocular hypertension.
in vivo
Dipivefrin hydrochloride (0.3-10 μg/kg; i.p.;) induces enhancement of memory involves central beta- but not alpha-adrenergic mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 64019-93-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,0,1 and 9 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 64019-93:
(7*6)+(6*4)+(5*0)+(4*1)+(3*9)+(2*9)+(1*3)=118
118 % 10 = 8
So 64019-93-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H
64019-93-8Relevant academic research and scientific papers
Enantiomeric separation and simulation study of eight anticholinergic drugs on an immobilized polysaccharide-based chiral stationary phase by HPLC
Li, Meng,Zhang, Bo,Yu, Jia,Wang, Jian,Guo, Xingjie
, p. 11724 - 11731 (2018/07/25)
The enantiomeric separation of eight anticholinergic drugs was first systematically examined on a derivative polysaccharide chiral stationary phase (CSP), i.e. Chiralpak ID in the normal phase mode. Except for scopolamine hydrobromide and benzhexol hydroc
