640238-28-4

Upstream product

• 98-88-4 benzoyl chloride 
• 5678-47-7 3-amino-3-(3-nitro-phenyl)-propionic acid 
• 1269634-20-9 C₁₇H₁₆N₂O₅ 
• 140373-38-2 methyl 3-amino-3-(3-nitrophenyl)propionate 
• 99-61-6 3-nitro-benzaldehyde 

Downstream Products

• 874656-85-6 4-(3-nitro-phenyl)-2-phenyl-4,5-dihydro-[1,3]oxazin-6-one 
• 1257211-85-0 (R)-1-[3-benzamido-3-(3-nitrophenyl)propanamido]-3-methylbutylboronic acid 

Relevant academic research and scientific papers

Synthesis, in vitro and in vivo biological evaluation, and comprehensive understanding of structure-activity relationships of dipeptidyl boronic acid proteasome inhibitors constructed from β-amino acids

An extensive structure-activity relationship (SAR) study of 72 dipeptidyl boronic acid proteasome inhibitors constructed fromβ -amino acids is reported. SAR analysis revealed that bicyclic groups at the R1 position, 3-F substituents at the Rsu

Kinetic resolution of oxazinones: An organocatalytic approach to enantiomerically pure β-amino acids

(Chemical Equation Presented) A profitable split: An organocatalytic resolution converts readily available racemic oxazinones 1 into valuable enantiomerically pure β-amino acid derivatives 2 (> 99% ee of the remaining 1 at 53% conversion; 88% ee of the ester 2). This catalytic ring-opening reaction requires as little as 1 mol% of the modular and readily accessible thiourea organocatalyst 3.