6404-26-8

Basic information

• Product Name: BOC-LYS(AC)-OH
• Synonyms: N^e-Acetyl-N^a-Boc-L-lysine, 98%;Boc-L-Lys(Ac)-OH;Nα-Boc-Nε-acetyl-L-lysine≥ 98% (HPLC);Nepsilon-Acetyl-Nalpha-Boc-L-lysine;BOC-N-EPSILON-ACETYL-L-LYSINE;BOC-LYSINE(AC)-OH;BOC-LYS(AC)-OH;N-ALPHA-T-BUTOXYCARBONYL-N-EPSILON-ACETYL-L-LYSINE
• CAS NO: 6404-26-8
• Molecular Formula: C₁₃H₂₄N₂O₅
• Molecular Weight: 288.34
• Product Categories: Lysine [Lys, K];Boc-Amino Acids and Derivative;Boc-Amino acid series
• Mol File: 6404-26-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 137-138 °C
• Boiling Point: 528.753 °C at 760 mmHg
• Flash Point: 273.58 °C
• Appearance: /
• Density: 1.125 g/cm³
• Vapor Pressure: 1.36E-12mmHg at 25°C
• Refractive Index: 1.479
• Storage Temp.: Store at 0-5°C
• PKA: 3.99±0.21(Predicted)
• CAS DataBase Reference: BOC-LYS(AC)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-LYS(AC)-OH(6404-26-8)
• EPA Substance Registry System: BOC-LYS(AC)-OH(6404-26-8)

Safety Data

• Hazardous Substances Data: 6404-26-8(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white powder

InChI:InChI=1/C13H24N2O5/c1-9(16)14-8-6-5-7-10(11(17)18)15-12(19)20-13(2,3)4/h10H,5-8H2,1-4H3,(H,14,16)(H,15,19)(H,17,18)/t10-/m0/s1

Upstream product

• 13734-28-6 Boc-Lys-OH 

Downstream Products

• 787549-23-9 (S)-[5-acetylamino-1-(2-oxo-4-trifluoromethyl-2H-chromen-7-ylcarbamoyl)pentyl]carbamic acid tert-butyl ester 
• 1171121-42-8 C₄₄H₅₇N₅O₉ 
• 1242276-49-8 C₂₇H₄₀N₄O₅ 
• 692-04-6 H-Lys(acetyl)-OH 
• 56-87-1 L-lysine 
• 13734-28-6 Boc-Lys-OH 
• 76491-59-3 1-O-benzyl-4,6-O-benzylidene-N-acetylmuramyl-alanyl-D-isoglutaminyl-N^ε-acetyllysyl-D-alanyl-pentaglycine amide 
• 444188-75-4 4-[2-((S)-5-Acetylamino-1-{(S)-1-[benzyloxy-((R)-1-benzyloxycarbonyl-ethoxy)-phosphoryl]-ethylcarbamoyl}-pentylcarbamoyl)-ethylcarbamoyl]-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 444188-74-3 (R)-2-({(S)-1-[(S)-6-Acetylamino-2-(3-tert-butoxycarbonylamino-propionylamino)-hexanoylamino]-ethyl}-benzyloxy-phosphinoyloxy)-propionic acid benzyl ester 

Relevant articles and documents

Degradation of 1-deoxy-d-erythro-hexo-2,3-diulose in the presence of lysine leads to formation of carboxylic acid amides

A novel species of amides formed from degradation of one of the most important key intermediates in Maillard hexose chemistry-1-deoxyhexo-2,3- diulose-was investigated. In 1-deoxyhexo-2,3-diulose/Nα-t-BOC- lysine reaction mixtures four amides, Nε-acetyl lysine, N ε-formyl lysine, Nε-lactoyl lysine and N ε-glycerinyl lysine, were identified and their structures verified by authentic reference standards. Amides and corresponding carboxylic acids (acetic acid, formic acid, lactic acid and glyceric acid) accumulated over time. Both Nε-lysine amides and carboxylic acids were thus determined as stable Maillard end products. Results of model incubations suggested the synthesis of amides to be mechanistically closely related to the formation of their corresponding carboxylic acids by β-dicarbonyl cleavage. Due to the different chemical properties of all the compounds monitored, various analytical strategies had to be carried out (LC-MS2, GC-MS, GC-FID, enzymatic determination).