64044-11-7 Usage
Description
(S)-PIPERAZINE-2-CARBOXYLIC ACID is a chemical compound that belongs to the class of piperazine carboxylic acids. It is an important intermediate in the synthesis of pharmaceuticals and agrochemicals, playing a crucial role in the production of various drugs, including antipsychotics, antihistamines, and antifungal agents. Additionally, it serves as a building block for the preparation of heterocyclic compounds and as a chelating ligand for metal ions, showcasing its wide range of applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
(S)-PIPERAZINE-2-CARBOXYLIC ACID is used as an intermediate in the synthesis of various drugs for the treatment of different medical conditions. Its role in the production of antipsychotics, antihistamines, and antifungal agents highlights its importance in the development of effective medications.
Used in Agrochemical Industry:
(S)-PIPERAZINE-2-CARBOXYLIC ACID is used as an intermediate in the synthesis of agrochemicals, contributing to the development of products that protect crops and enhance agricultural productivity.
Used in Heterocyclic Compound Preparation:
(S)-PIPERAZINE-2-CARBOXYLIC ACID is used as a building block for the preparation of heterocyclic compounds, which are essential components in various chemical and pharmaceutical applications.
Used as a Chelating Ligand for Metal Ions:
(S)-PIPERAZINE-2-CARBOXYLIC ACID is used as a chelating ligand for metal ions, enabling the formation of stable complexes that are useful in various chemical processes and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 64044-11-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,0,4 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 64044-11:
(7*6)+(6*4)+(5*0)+(4*4)+(3*4)+(2*1)+(1*1)=97
97 % 10 = 7
So 64044-11-7 is a valid CAS Registry Number.
64044-11-7Relevant articles and documents
Synthesis of cyclic α-hydrazino acids
Duttagupta, Indranil,Goswami, Koushik,Sinha, Surajit
experimental part, p. 8347 - 8357 (2012/09/21)
Synthesis of five-, six-, seven-, eight-, and nine-membered cyclic α-hydrazino acids from a common starting material 'diethylmalonate' with 26, 16, 34, 13.5, and 13.33% overall yields is described. Sequential allylation or homoallylation and electrophilic amination followed by cyclization gave the desired rings. The methyl esters of eight- and nine-membered rings were synthesized by RCM and the corresponding free acids were generated after hydrolysis in the presence of 1 M BBr3 solution in DCM.
Chloptosin, an apoptosis-inducing dimeric cyclohexapeptide produced by Streptomyces
Umezawa, Kazuo,Ikeda, Yoko,Uchihata, Yuki,Naganawa, Hiroshi,Kondo, Shinichi
, p. 459 - 463 (2007/10/03)
In the course of screening for apoptosis-inducing agents, chloptosin (1) was isolated from the culture broth of Streptomyces. The dumbbell-type structure of the dimeric cyclohexapeptide consisting of D-valine, (3S)- and (3R)-piperazic acids, O-methyl-L-serine, D-threonine, and (2S,3aR,8aR)-6- chloro-3a-hydroxy-2,3,3a,8a-hexahydropyrrolo[2,3-b]indole-2-carboxylic acid was elucidated by spectroscopic and chemical degradation studies. The amino acid components in each cyclohexapeptide domain were presented in alternating R and S configurations. Chloptosin (1) was found to induce apoptotic activity in apoptosis-resistant human pancreatic adenocarcinoma cell line AsPC-1 and showed a strong antimicrobial activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus.