64054-49-5

Upstream product

• 62020-12-6 4-benzyloxy-5-(4-fluorophenoxy)-1-pentanol 
• 62020-20-6 4-benzyloxy-5-(4-fluorophenoxy)-1-pentene 
• 62020-11-5 5-(4-fluorophenoxy)-1-penten-4-ol 
• 59769-37-8 2-(4-Fluorophenoxy)-acetaldehyde Diethyl Acetal 
• 59769-38-9 2-(4-fluorophenoxy)acetaldehyde 
• 371-41-5 4-Fluorophenol 

Downstream Products

• 64054-51-9 7-{2-[4-(4-fluoro-phenoxy)-3-hydroxy-butyl]-1,1,4-trioxo-1λ⁶-thiazolidin-3-yl}-heptanoic acid 
• 64054-58-6 7-{2-[3-benzyloxy-4-(4-fluoro-phenoxy)-butyl]-1,1,4-trioxo-1λ⁶-thiazolidin-3-yl}-heptanoic acid benzyl ester 

Relevant academic research and scientific papers

Certain thiazolidine compounds

This invention relates to novel 8-aza-9-oxo-11-thia-, -11-oxothia-, and -11-dioxothia-prostanoic acid compounds, salts, and derivatives thereof and also to processes for the preparation of such compounds. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators, for the treatment of certain autoimmune diseases, and in preventing thrombus formation.

Prostaglandin isosteres. 1. (8-Aza-, 8,10-diaza-, and 8-aza-11-thia)-9-oxoprostanoic acids and their derivatives.

A series of novel (8-aza-, 8,10-diaza-, and 8-aza-11-thia)-9-oxoprostanoic acids has been synthesized and evaluated for their ability to mimic the E series prostaglandins in stimulating cAMP formation in the mouse ovary and in binding to the rat kidney pl