64068-12-8 Usage
Uses
Used in Pharmaceutical Industry:
(6-chloro-8-methylimidazo[1,2-b]pyridazin-2-yl)acetic acid is utilized as a key intermediate in the synthesis of pharmaceuticals for its potential medicinal properties. Its complex structure allows for the development of drugs that can target specific biological pathways or receptors, offering novel treatment options for various diseases and conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (6-chloro-8-methylimidazo[1,2-b]pyridazin-2-yl)acetic acid serves as a valuable compound for studying the structure-activity relationships of imidazo[1,2-b]pyridazine derivatives. This helps researchers understand how modifications to the molecule can influence its biological activity, potentially leading to the discovery of more effective and safer drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 64068-12-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,0,6 and 8 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 64068-12:
(7*6)+(6*4)+(5*0)+(4*6)+(3*8)+(2*1)+(1*2)=118
118 % 10 = 8
So 64068-12-8 is a valid CAS Registry Number.
64068-12-8Relevant academic research and scientific papers
Research on heterocyclic compounds. XXXIII-synthesis and analgesic activity of imidazo[1,2-b]pyridazine-2-acetic acid derivatives
Luraschi,Arena,Sacchi,Laneri,Abignente,D'Amico,Berrino,Rossi
, p. 349 - 354 (2007/10/02)
A series of imidazo[1,2-b]pyridazine-2-acetic esters, acids and amides was synthesized and tested for antiinflammatory, analgesic and ulcerogenic activities. The ethyl esters were prepared by cyclocondensation of some 3-aminopyridazines with ethyl 4-chloroacetoacetate, followed by hydrolysis or amminolysis in order to obtain the corresponding acids and amides. The capacity of inhibiting the sarrageenan-induced edema in the rat paw and the writhes induced by acetic acid in mice were evaluated, as well as the ulcerogenic action in rats. The acid is derivatives showed significant analgesic activity which is comparable to that found in other series of imidazo[1,2-b]pyridazine analogs previously examined.
