640727-45-3Relevant academic research and scientific papers
Asymmetric Intramolecular Allylic Amination: Straightforward Approach to Chiral C1-Substituted Tetrahydroisoquinolines
Ito, Katsuji,Akashi, Suemi,Saito, Bunnai,Katsuki, Tsutomu
, p. 1809 - 1812 (2007/10/03)
Newly introduced Pd-catalyzed asymmetric intramolecular allylic amination provides an easy access to pharmaceutically important 1-substituted tetrahydroisoquinolines. With this amination as the key step, (R)-carnegine was synthesized in an enantioselectiv
