641-90-7 Usage
General Description
2-hydroxyemodin, also known as emodin-2-ol, is a naturally occurring anthraquinone derivative found in several plant species, including rhubarb and knotweed. This chemical compound has been associated with various biological activities, including anti-inflammatory, antioxidant, and anticancer properties. 2-hydroxyemodin has been studied for its potential therapeutic effects, such as its ability to inhibit cell proliferation, induce apoptosis, and suppress tumor growth. It has also been investigated for its role in regulating immune responses and reducing inflammation. Additionally, 2-hydroxyemodin has been explored as a potential treatment for skin diseases and microbial infections due to its antimicrobial and antifungal properties. Overall, research on this chemical compound suggests it has promising medicinal applications and warrants further investigation for its potential health benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 641-90-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,4 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 641-90:
(5*6)+(4*4)+(3*1)+(2*9)+(1*0)=67
67 % 10 = 7
So 641-90-7 is a valid CAS Registry Number.
641-90-7Relevant articles and documents
The Chemical Structure and the Mutagenicity of Emodin Metabolites
Morooka, Nobuhisa,Nakano, Sonoko,Itoi, Noriko,Ueno, Yoshio
, p. 1247 - 1252 (2007/10/02)
Emodin (1,3,8-trihydroxy-6-methyl-9,10-anthraquinone) is a natural occuring anthraquinone formed in rhubarb and fungal metabolites.Emodin was transformed into 6 major metabolites by rat hepatic microsomes.The metabolites were identified as 2-hydroxyemodin, 4-hydroxyemodin, 5-hydroxyemodin, 7-hydroxyemodin, ω-hydroxyemodin, and emodic acid by comparison with the synthetic compounds using thin-layer chromatography.It was clear that 2-hydroxyemodin is a proximate mutagen as a synthetic compound by the Salmonella assay.Other metabolites, such as 5-hydroxyemodin and ω-hydroxyemodin, became active after metabolic activation, but 4-hydroxyemodin and emodic acid were inactive either in the presence or in the absence of the metabolic activation system.
