641-92-9

Upstream product

• 88453-79-6 7,10-di-O-methyl-ξ-pyrromycinone 
• 88453-81-0 10(R,S)-(methoxycarbonyl)-9(R,S)-ethyl-9(R,S)-hydroxy-7,8,9,10-tetrahydro-1,4,6-trimethoxy-5,12-naphthacenedione 
• 88453-76-3 methyl <3-(3-hydroxypent-1-yl)-4,5,8-trimethoxyanthraquinon-2-yl>acetate 
• 88453-78-5 methyl <3-(3-oxopent-1-yl)-4,5,8-trimethoxyanthraquinon-2-yl>acetate 
• 88453-73-0 methyl 2-<3-(3-(benzyloxy)pent-1-yl)-5,8-dimethoxy-4-hydroxyanthraquinon-2-yl>acetate 
• 88453-75-2 methyl <3-(3-(benzyloxy)pent-1-yl)-4,5,8-trimethoxyanthraquinon-2-yl>acetate 
• 76696-04-3 5,8-di-O-methyl-helminthosporin 
• 96303-29-6 1-hydroxy-2-hydroxymethyl-5,8-dimethoxy-3-methyl-9,10-anthraquinone 
• 96303-31-0 2-chloromethyl-1-hydroxy-5,8-dimethoxy-3-methyl-9,10-anthraquinone 
• 96303-37-6 1-hydroxy-5,8-dimethoxy-3-methyl-2-(3-oxopentyl)-9,10-anthraquinone 
• 96303-73-0 1-hydroxy-3-hydroxymethyl-5,8-dimethoxy-2-(3-oxopentyl)-9,10-anthraquinone 
• 96303-40-1 5,8-dimethoxy-1-(2,2-dimethyl-1-propionyloxy)-3-methyl-2-(3-oxopentyl)-9,10-anthraquinone 
• 88453-77-4 methyl <5,8-dimethoxy-4-hydroxy-3-(3-oxopent-1-yl)anthraquinon-2-yl>acetate 
• 96303-43-4 3-bromomethyl-5,8-dimethoxy-1-(2,2-dimethylpropionyloxy)-2-(3-oxopentyl)-9,10-anthraquinone 

Downstream Products

• 21288-61-9 (+/-)-ε-pyrromycinone 

Relevant academic research and scientific papers

SYNTHESIS OF ξ-PYRROMYCINONE, 7-DEOXYAURAMYCINONE, AND 7-DEOXYAKLAVINONE VIA KETOESTER CYCLIZATION

7,10-O-Dimethyl-ξ-pyrromycinone (78) and the not naturally occurring 7-deoxyanthracyclinones 76 and 77 are prepared via base induced cyclization of the ketoesters 73-75, and stereoselectively hydroxylated to the 2,4-cis diols 83 and 85.

Regiospecific Total Syntheses of (+/-)-Aklavinone and (+/-)-ε-Pyrromycinone from a Common Synthon

The preparation and use of cyclohexenone 10 as a common intermediate for regiospecific total synthesis of both (+/-)-aklavinone (1a) and (+/-)-ε-pyrromycinone (2a) is described.