64107-58-0 Usage
Molecular structure
The compound consists of a pyrimidine ring with a thiazole ring attached to it, and an imidazole ring attached to a sulfanylethylamino group.
Salt form
The compound is in the form of trihydrochloride salt, which refers to the presence of three chloride ions (Cl-) combined with the parent compound.
Potential pharmaceutical applications
The compound may have activity as an anti-infective, antifungal, or antiparasitic agent due to its complex structure and potential high affinity for certain receptors or enzymes.
Suitability as a drug candidate
The compound's complex structure and potential activity against various pathogens make it a promising candidate for further investigation in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 64107-58-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,1,0 and 7 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 64107-58:
(7*6)+(6*4)+(5*1)+(4*0)+(3*7)+(2*5)+(1*8)=110
110 % 10 = 0
So 64107-58-0 is a valid CAS Registry Number.
64107-58-0Relevant articles and documents
Isocytosine H2-receptor histamine antagonists II. Synthesis and evaluation of biological activity at histamine H1- and H2-receptors of 5-(heterocyclyl)methylisocytosines
Brown, Thomas H.,Blakemore, Robert C.,Blurton, Peter,Durant, Graham J.,Ganellin, C. Robin,et al.
, p. 65 - 72 (2007/10/02)
A series of 2--4-pyrimidones was synthesized based on oxmetidine 2, in which the methylenedioxyphenyl group of 2 was replaced by a heterocyclic ring.Good H2-receptor antagonist activity was retained over a range of basic and neutral heterocyclic substituents.Replacement of the 5-methyl-4-imidazolyl ring in selected compounds with 2-thiazolyl and, particularly, 3-bromo-2-pyridyl rings gave a series of compounds which have both H1- and H2-receptor histamine antagonist activities.Some structure-activity and structure-toxicity correlations are discussed.Compound 6d, 2--5-(6-methylpyrid-3-yl)-4-pyrimidone, has the most favourable combination of properties for H2-antagonism and has been evaluated further as an anti-secretory agent.