64107-71-7

Basic information

• Product Name: (4aR,8aR)-3-methyl-4a,5,6,7,8,8a-hexahydro[1,3]thiazolo[3,2-a]benzimidazole hydrochloride
• CAS NO: 64107-71-7
• Molecular Formula: C₁₀H₁₅ClN₂S
• Molecular Weight: 230.7575
• Mol File: 64107-71-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 306.5°C at 760 mmHg
• Flash Point: 139.2°C
• Vapor Pressure: 0.000769mmHg at 25°C
• CAS DataBase Reference: (4aR,8aR)-3-methyl-4a,5,6,7,8,8a-hexahydro[1,3]thiazolo[3,2-a]benzimidazole hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (4aR,8aR)-3-methyl-4a,5,6,7,8,8a-hexahydro[1,3]thiazolo[3,2-a]benzimidazole hydrochloride(64107-71-7)
• EPA Substance Registry System: (4aR,8aR)-3-methyl-4a,5,6,7,8,8a-hexahydro[1,3]thiazolo[3,2-a]benzimidazole hydrochloride(64107-71-7)

Safety Data

• Hazardous Substances Data: 64107-71-7(Hazardous Substances Data)

Upstream product

• 30086-64-7 cis-2-thiohexahydrobenzimidzole 
• 78-95-5 chloroacetone 
• 30086-64-7 trans-2-thiohexahydrobenzimidazole 
• 1121-22-8 trans-1,2-Diaminocyclohexane 
• 1436-59-5 cis-cyclohexane-1,2-diamine 

Relevant articles and documents

Effect of Structural Change on Acute Toxicity and Antiinflammatory Activity in a Series of Imidazothiazoles and Thiazolobenzimidazoles

The effect of structural change on the biological activity of a series of imidazothiazoles and thiazolobenzimidazoles is described.It was found that compounds with polar substituents at the 2 or 3 position of the ring system are less acutely toxic while maintaining antiinflammatory activity.Other structural changes, such as the incorporation of a gem-dimethyl substituent in the 6 position, increase acute toxicity and eliminate antiinflammatory activity.The compound with the best activity/toxicity ratio contains an alkyl sulfonyl substituent on the thiazole ring.The thiazolobenzimidazole analogues are more potent than the imidazole analogues.