64125-02-6

Basic information

• Product Name: 1,4,2-Dioxazole-5-acetic acid, 3-(4-bromophenyl)-5-(methoxycarbonyl)-, methyl ester
• CAS NO: 64125-02-6
• Molecular Formula: C13H12BrNO6
• Molecular Weight: 358.145
• Mol File: 64125-02-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,4,2-Dioxazole-5-acetic acid, 3-(4-bromophenyl)-5-(methoxycarbonyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4,2-Dioxazole-5-acetic acid, 3-(4-bromophenyl)-5-(methoxycarbonyl)-, methyl ester(64125-02-6)
• EPA Substance Registry System: 1,4,2-Dioxazole-5-acetic acid, 3-(4-bromophenyl)-5-(methoxycarbonyl)-, methyl ester(64125-02-6)

Safety Data

• Hazardous Substances Data: 64125-02-6(Hazardous Substances Data)

Upstream product

• 619-42-1 4-methoxycarbonylphenyl bromide 
• 1836-27-7 4-bromo-N-hydroxybenzamide 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 1836-27-7 4-Brom-benzhydroxamsaeure 

Relevant articles and documents

Vinylphosphonium Salt-Mediated Reactions: A One-Pot Condensation Approach for the Highly cis-Selective Synthesis of N-Benzoylaziridines and the Green Synthesis of 1,4,2-Dioxazoles as Two Important Classes of Heterocyclic Compounds

An efficient, one-pot, and convenient approach for the reaction of the same precursors, trialkyl(aryl) phosphines, acetylene diesters, and benzhydroxamic acids has been developed to produce two important classes of heterocyclic compounds: N-benzoylaziridines and 1,4,2-dioxazoles. The strategy utilizes the intermediate solvation as a key step in product selectivity. The usefulness of the developed approach has been confirmed in the unprecedented highly cis-selective formation of the N-benzoylaziridines. In addition, the procedure provides a green alternative method for the synthesis of 1,4,2-dioxazoles employing a β-cyclodextrin nanoreactor in aqueous media.