64135-24-6Relevant academic research and scientific papers
Synthesis and antinematodal activity of 3-n-alkylphenols
Takaishi, Kazuto,Alen, Yohannes,Kawazu, Kazuyoshi,Baba, Naomichi,Nakajima, Shuhei
, p. 2398 - 2400 (2007/10/03)
Several 3-alkylphenols including 3-undecylphenol, which was isolated from a Sumatran rainforest plant, were synthesized to investigate their antinematodal activity against the phytopathogenic nematodes, Bursapherencus xylophilus. A three-step synthesis involving the treatment of 2-cyclohexen-1-one with the Grignard reagent, oxidation of the resulting 1-alkyl-2-cyclohexen-1-ol and subsequent aromatization of 3-alkyl-2-cyclohexen-1-one successfully afforded such phenols. Among the 3-alkylphenols, 3-nonylphenol showed the highest activity, while 3-decylphenol and 3-undecylphenol also showed high activity.
A Versatile One-pot Procedure for the Insertion of a 3-Substituent into 2-Cycloalkenones
Katritzky, Alan R.,Soloducho, Jadwiga,Musgrave, Richard P.,Breytenbach, Jaco C.
, p. 5491 - 5494 (2007/10/02)
1-Trimethylsilylbenzotriazole was used to form 1,4-adducts with 2-cycloalkenones which were treated in situ with base and electrophile to give, upon hydrolysis, a variety of 3-substituted 2-cycloalkenones in moderate yield.
