6414-58-0

Basic information

• Product Name: DIETHYL 2-ANILINOMALONATE
• Synonyms: DIETHYL 2-ANILINOMALONATE;DIETHYL 2-PHENYLAMINOMALONATE;2-(Phenylamino)propanedioic acid diethyl ester;2-Anilinomalonic acid diethyl ester;2-Phenylamino-malonic acid diethyl ester;Diethyl 2-(phenylamino);diethyl 2-anilinopropanedioate
• CAS NO: 6414-58-0
• Molecular Formula: C₁₃H₁₇NO₄
• Molecular Weight: 251.27838
• Mol File: 6414-58-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 340.6°C at 760 mmHg
• Flash Point: 159.8°C
• Appearance: /
• Density: 1.167g/cm³
• Vapor Pressure: 8.52E-05mmHg at 25°C
• Refractive Index: 1.536
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: DIETHYL 2-ANILINOMALONATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYL 2-ANILINOMALONATE(6414-58-0)
• EPA Substance Registry System: DIETHYL 2-ANILINOMALONATE(6414-58-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 6414-58-0(Hazardous Substances Data)

Usage

General Description

DIETHYL 2-ANILINOMALONATE is a chemical compound with the molecular formula C17H19NO4. It is a colorless to light yellow liquid with a sweet, fruity odor. DIETHYL 2-ANILINOMALONATE is commonly used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. It is also used as a building block in the production of various fine chemicals and active pharmaceutical ingredients. DIETHYL 2-ANILINOMALONATE is known for its ability to undergo various chemical reactions, making it a versatile and important compound in the field of organic synthesis. It is important to handle this compound with caution and adhere to proper safety guidelines, as it may be harmful if swallowed, inhaled, or in contact with skin.

InChI:InChI=1/C13H17NO4/c1-3-17-12(15)11(13(16)18-4-2)14-10-8-6-5-7-9-10/h5-9,11,14H,3-4H2,1-2H3

Upstream product

• 103-71-9 phenyl isocyanate 
• 14064-10-9 diethyl 2-chloromalonate 
• 62-53-3 aniline 
• 685-87-0 Diethyl 2-bromomalonate 
• 4303-49-5 diethyl [²H₂]malonate 
• 105-53-3 diethyl malonate 
• 5256-74-6 1,3-diethyl 2-diazopropanedioate 
• 102-07-8 bis(diphenyl)urea 

Downstream Products

• 56598-97-1 1,3-diphenyl-5-carbethoxyhydantoin 
• 5634-74-2 Diethyl (2-chloro-N-phenylacetamido)malonate 
• 56599-01-0 diethyl-N,N'-diphenylureidomalonate 
• 83304-67-0 3-Hydroxy-3-methyl-5-oxo-1-phenyl-pyrrolidine-2,2-dicarboxylic acid diethyl ester 
• 34642-61-0 diethyl 2-(2-bromo-N-phenylacetamido)malonate 
• 140429-79-4 diethyl N-phenyl-N'-(4-chlorophenyl) ureidomalonate 
• 88100-56-5 1-phenyl-3-(4-chlorophenyl)-5-carbethoxyhydantoin 
• 131843-52-2 Diethyl 2-(2-Chloro-N-phenylpropanamido)malonate 
• 5634-79-7 ω-Brompropionanilido-malonsaeure-diaethylester 
• 62851-28-9 5-oxo-1,3-diphenyl-pyrrolidine-2,2-dicarboxylic acid diethyl ester 
• 63931-37-3 2-[(2-Amino-4-chloro-benzoyl)-phenyl-amino]-malonic acid diethyl ester 
• 63931-43-1 2-[(2-Amino-benzoyl)-phenyl-amino]-malonic acid diethyl ester 
• 855269-32-8 1-cyclohexyl-4-oxo-azetidine-2,2-dicarboxylic acid diethyl ester 
• 96296-41-2 4-oxo-1-phenyl-azetidine-2,2-dicarboxylic acid monoethyl ester 

Relevant articles and documents

Continuous-flow electro-oxidative coupling of sulfides with activated methylene compounds leading to sulfur ylides

An unprecedentedly straightforward electro-oxidative coupling of sulfides with activated methylene compounds to synthesize sulfur ylides has been developed. Good to excellent yields can be obtained under catalyst- and oxidant-free conditions at room tempe

A convenient synthesis of 3-phenylthio-azetidin-2-ones

3-Phenylthio-4,4-diethoxycarbonyl-azetidin-2-ones 8 have been conveniently synthesised by reacting 2-chlorophenylthioacetyl chloride 5 with aryl substituted aminomalonates 7 under mild basic conditions. Alternatively, C-3 alkylation of azetidin-2-one usin