641612-91-1

Upstream product

• 540-37-4 p-aminoiodobenzene 
• 126063-08-9 2,2,2-trifluoro-N-(4-iodophenyl)acetamide 
• 74-88-4 methyl iodide 

Downstream Products

• 60577-34-6 p-iodo-N-methylaniline 
• 1346654-69-0 2,2,2-trifluoro-N-(4-(5-hydroxypent-1-yn-1-yl)phenyl)-N-methylacetamide 
• 1346654-76-9 5-(4-(methylamino)phenyl)pent-4-yn-1-ol 

Relevant academic research and scientific papers

BI-FUNCTIONAL QUINOLINE ANALOGS

Provided are compounds of Formula I: wherein X is: R1 and R2 together with the phenyl to which they are bound may form a bicyclic, fused heterocyclic ring, and all other variables are as defined herein, as well as their use in treating pulmonary inflammation or bronchoconstriction and compositions comprising and processes for preparing the same.

Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors

The present application describes sulfonylaminovalerolactams and derivatives thereof of Formula I: or pharmaceutically acceptable salt forms thereof, wherein ring G is a mono- or bicyclic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.