641620-70-4

Upstream product

• 98-80-6 phenylboronic acid 

Downstream Products

• 1246754-94-8 (S)-(+)-N-[phenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]acetamide 
• 1351866-47-1 (R)-(+)-N-[(4-trifluoromethylphenyl)(phenyl)methyl]acetamide 
• 1351866-39-1 (R)-(+)-N-[(4-methylphenyl)(phenyl)methyl]acetamide 
• 1246754-95-9 (S)-(-)-N-[(4-methylphenyl)(phenyl)methyl]acetamide 
• 1351866-48-2 (R)-(+)-N-[(2-methylphenyl)(phenyl)methyl]acetamide 
• 1351866-42-6 (S)-(+)-N-[(2-methylphenyl)(phenyl)methyl]acetamide 

Relevant academic research and scientific papers

(S)-(+)-N-Acetylphenylglycineboronic Acid: A Chiral Derivatizing Agent for Ee Determination of 1,2-Diols

(Equation Presented) A new chiral derivatizing agent for ee determination of 1,2-diols via 1H NMR is described. (S)-(+)-N- Acetylphenylglycineboronic acid (1) is synthesized in enantiomerically pure form; its reaction with chiral diols quantitatively yields cyclic boronic esters 5a-g. The latter show a remarkably high diastereodifferentiation of proton NMR signals useful for de determination.

Inversion or retention? Effects of acidic additives on the stereochemical course in enantiospecific suzuki-miyaura coupling of α-(acetylamino) benzylboronic esters

The stereochemical course of the stereospecific Suzuki-Miyaura coupling of enantioenriched α-(acetylamino)benzylboronic esters with aryl bromides can be switched by the choice of acidic additives in the presence of a Pd/XPhos catalyst system. Highly enant