641636-54-6

Basic information

• Product Name: 2-acetylamino-3-(4-ethoxycarbonylmethoxy-3-hydroxy-phenyl)-propionic acid
• Synonyms: 2-acetylamino-3-(4-ethoxycarbonylmethoxy-3-hydroxy-phenyl)-propionic acid
• CAS NO: 641636-54-6
• Molecular Weight: 325.318
• Mol File: 641636-54-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-acetylamino-3-(4-ethoxycarbonylmethoxy-3-hydroxy-phenyl)-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-acetylamino-3-(4-ethoxycarbonylmethoxy-3-hydroxy-phenyl)-propionic acid(641636-54-6)
• EPA Substance Registry System: 2-acetylamino-3-(4-ethoxycarbonylmethoxy-3-hydroxy-phenyl)-propionic acid(641636-54-6)

Safety Data

• Hazardous Substances Data: 641636-54-6(Hazardous Substances Data)

Upstream product

• 641636-58-0 (2-benzyloxy-4-bromo-phenoxy)-acetic acid ethyl ester 
• 6272-38-4 O-benzylcatechol 

Downstream Products

• 918657-87-1 2-{4-[2-acetylamino-3-(4-carboxymethoxy-3-hydroxy-phenyl)-propionylamino]-butoxy}-6-hydroxy-benzoic acid methyl ester 

Relevant articles and documents

Identification of a monoacid-based, cell permeable, selective inhibitor of protein tyrosine phosphatase 1B

Monoacid-based PTP1B inhibitors with improved physiochemical properties have been investigated. A (2-hydroxy-phenoxy) acetic acid-based phosphotyrosyl mimetic has been linked with an optimized second arylphosphate binding site ligand to produce compound 20 with low micromolar potency against PTP1B, good selectivity over TCPTP (20-fold) and high cell permeability in the Caco-2 system.