64173-00-8

Basic information

• Product Name: 1,3-Piperazinedicarboxylic acid, 4-(2-nitrophenyl)-, 1-(phenylmethyl) ester
• CAS NO: 64173-00-8
• Molecular Formula: C19H19N3O6
• Molecular Weight: 385.376
• Mol File: 64173-00-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,3-Piperazinedicarboxylic acid, 4-(2-nitrophenyl)-, 1-(phenylmethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Piperazinedicarboxylic acid, 4-(2-nitrophenyl)-, 1-(phenylmethyl) ester(64173-00-8)
• EPA Substance Registry System: 1,3-Piperazinedicarboxylic acid, 4-(2-nitrophenyl)-, 1-(phenylmethyl) ester(64173-00-8)

Safety Data

• Hazardous Substances Data: 64173-00-8(Hazardous Substances Data)

Upstream product

• 1493-27-2 ortho-nitrofluorobenzene 
• 934630-06-5 4-(benzyloxy-carbonyl)-2-piperazinecarboxylic acid 
• 501-53-1 benzyl chloroformate 
• 67889-51-4 4-[(benzyloxy)carbonyl]-2-piperazinecarboxylic acid copper 

Downstream Products

• 444161-48-2 benzyl 8-bromo-5-oxo-1,2,4,4a,5,6-hexahydro-3H-pyrazino-[1,2-a]quinoxaline-3-carboxylate 
• 64173-01-9 3-benzyloxycarbonyl-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one 
• 304023-32-3 6-methyl-5-oxo-1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinoxaline-3-carboxylic acid benzyl ester 
• 75704-19-7 2,3,4,4a-tetrahydro-1H-pyrazino<1,2a>quinoxalin-5(6H)-one 

Relevant articles and documents

Tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them

Compounds of formula (I): wherein A represents a 5, 6 or 7-membered (hetero)aromatic or non-aromatic ring,n and n′ represent 0, 1 or 2X represents an alkylene chain as defined in the description,R3 represents an aryl or heteroaryl group,one of the groups R1 and R2 represents a hydrogen atom and the other represents a group of formula (II) as defined in the description. Medicinal products containing the same which are useful in treating conditions involving a defect in apoptosis.

Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-Tetrahydro-1H-pyrazino[1,2-a]quinozalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino [1,2-,a] quinoxalines

A series of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro- 1H-pyrazino[1,2-a]-quinoxalines was shown to exhibit 5-HT(2C) agonist binding and functional activity. Compound 21R inhibited food intake over 2 h in fasted, male Sprague-Dawley rats with ED50 values of 2 mg/kg (ip) and 10 mg/kg (po). (C) 2000 Elsevier Science Ltd.