64187-30-0Relevant academic research and scientific papers
Photochemical protection of amines with Cbz and Fmoc groups
Helgen, Celine,Bochet, Christian G.
, p. 2483 - 2486 (2007/10/03)
The photochemical conversion of amines into carbamates was achieved using N-Cbz-, N-Fmoc-, and N-Boc-5,7-dinitroindolines. This reaction allows the protection of amines in neutral medium. Primary and unhindered secondary amines were protected to yield their benzyloxycarbonyl- and 9-fluorenylmethoxycarbonyl derivatives efficiently, whereas bulky amines or anilines gave low yields or no product. On the other hand, the formation of N-Boc compounds, although possible, proceeded only with low yields.
Conversion of carbonimidodithioates to carbamates
Anbazhagan, Mariappan,Reddy, T. Indrasena,Rajappa, Srinivasachari
, p. 1623 - 1627 (2007/10/03)
Carbonimidodithioates derived from primary amines or α-amino acid esters have been converted to N-benzyloxycarbonyl derivatives under mild conditions by treatment first with sodium benzyl alcoholate and then with water. N-Benzyloxycarbonyl α-amino acids have been generated from the methyl esters by alkaline hydrolysis or from the allyl esters by Pd0-catalysed de-allylation.
