6419-69-8 Usage
General Description
4-Chloro-N-(2-Hydroxyethyl)benzenesulfonamide, often referred to by its Chemical Abstracts Service (CAS) Number 23904-37-4, is a chemical compound known for its applications across different scientific and industrial fields. As an intermediate in organic synthesis, it plays a crucial role in the production of a wide range of chemical products. Not much information is available about its safety and toxicity properties, highlighting a potential need for more research in this area. Its physical properties, such as its appearance, density, and melting and boiling points, may vary depending on the conditions it's kept or used in.
Check Digit Verification of cas no
The CAS Registry Mumber 6419-69-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,1 and 9 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6419-69:
(6*6)+(5*4)+(4*1)+(3*9)+(2*6)+(1*9)=108
108 % 10 = 8
So 6419-69-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H10ClNO3S/c9-7-1-3-8(4-2-7)14(12,13)10-5-6-11/h1-4,10-11H,5-6H2
6419-69-8Relevant articles and documents
Chemistry of Sulfonyl Isocyanates and Sulfonyl Isothiocyanates. IX. Routes to Substituted Oxazolidin-2-ones and Oxazolidine-2-thiones
McFarland, J. W.,Hayes, C. E.,Blair, E. B.,Stuhlmacher, K. R.
, p. 271 - 272 (2007/10/02)
4-Chlorobenzenesulfonyl isocyanate (I) reacted with 2-chloroethanol and 1-chloro-2-propanol to give, respectively, 2-choroethyl-4-chlorobenzenesulfonyl carbamate (III) and 1-chloro-2-propyl-4-chlorobenzenesulfonyl carbamate (VI).The carbamates III and VI cyclized under the influence of pyridine to afford, respectively, 3-(4-chlorobenzenesulfonyl)oxazolidin-2-one (IV) and 3-(4-chlorobenzenesulfonyl)-5-methyloxazolidin-2-one (VII).The oxazolidin-2-ones were stable toward hydrochloric acid but hydrolyzed in 2M sodium hydroxide solution to N-(2-hydroxyethyl)-4-chlorobenzenesulfonamide (V) and N-(2-hydroxy-1-propyl)-4-chlorobenzenesulfonamide (VIII), respectively. 4-Toluenesulfonyl isothiocyanate (II) reacted with 2-chloroethanol to give 2-chloroethyl-4-chlorobenzenesulfonyl thiocarbamate (IX), which was converted by pyridine to 3-(4-toluenesulfonyl)oxazolidine-2-thione. (X).
