64224-64-2Relevant academic research and scientific papers
A facile synthesis of 5-halopyrimidine-4-carboxylic acid esters via a Minisci reaction
Regan, Collin F.,Pierre, Fabrice,Schwaebe, Michael K.,Haddach, Mustapha,Jung, Michael E.,Ryckman, David M.
experimental part, p. 443 - 447 (2012/03/11)
This paper reports the synthesis of various 5-halopyrimidine-4-carboxylic acid esters via the Minisci homolytic alkoxycarbonylation of 5-halopyrimidines. The reaction was found to be highly regioselective, allowing the one-step synthesis of useful amounts
1,2-Dithiole derivatives
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, (2008/06/13)
1,2-Dithiole derivatives of the formula: STR1 WHEREIN Het represents an aromatic heterocyclic radical with six atoms in the ring two of which are nitrogen atoms, the heterocyclic radical optionally carrying a single substituent selected from halogen, alkyl, alkoxy, mercapto, alkylthio, dialkylamino, pyrrolidin-1-yl, piperidino, morpholino and 4-alkylpiperazin-1-yl and R represents halogen, alkyl (optionally substituted by alkoxycarbonyl), carboxy, alkoxycarbonyl, carbamoyl, N-alkylcarbamoyl or a group R1 --C(OH)-- in which R1 represents hydrogen or alkyl, the said alkyl, alkoxy and alkylthio radicals or alkyl or alkoxy moieties containing 1 to 4 carbon atoms except in the case of R1 which contains 1 to 3 carbon atoms when an alkyl radical, are new compounds useful in the treatment of bilharziasis.
