64228-84-8 Usage
Uses
Used in Pharmaceutical Industry:
2(1H)-ISOQUINOLINEPROPANOIC ACID,1-[(3,4-DIMETHOXYPHENYL)METHYL]-3,4-DIHYDRO-6,7-DIMETHOXY-, 1,5-PENTANEDIYL ESTER, (R,R)-(-)-, ETHANEDIOATE is used as an intermediate in the synthesis of pharmaceutical compounds for its unique structural features and potential biological activity.
Used in Chemical Research:
In the field of chemical research, 2(1H)-ISOQUINOLINEPROPANOIC ACID,1-[(3,4-DIMETHOXYPHENYL)METHYL]-3,4-DIHYDRO-6,7-DIMETHOXY-, 1,5-PENTANEDIYL ESTER, (R*,R*)-(-)-, ETHANEDIOATE serves as a valuable subject for studying the synthesis, properties, and potential applications of complex organic molecules. Its unique structure and stereochemistry make it an interesting target for exploration in academic and industrial research settings.
Used in Impurity Analysis:
As a derivative and potential impurity of Atricurium (A794500), a neuromuscular blocking agent, 2(1H)-ISOQUINOLINEPROPANOIC ACID,1-[(3,4-DIMETHOXYPHENYL)METHYL]-3,4-DIHYDRO-6,7-DIMETHOXY-, 1,5-PENTANEDIYL ESTER, (R,R)-(-)-, ETHANEDIOATE is utilized in the analysis and quality control of pharmaceutical products to ensure their safety and efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 64228-84-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,2,2 and 8 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 64228-84:
(7*6)+(6*4)+(5*2)+(4*2)+(3*8)+(2*8)+(1*4)=128
128 % 10 = 8
So 64228-84-8 is a valid CAS Registry Number.
64228-84-8Relevant academic research and scientific papers
Method for synthesizing cisatracurium besilate
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, (2021/03/06)
The invention discloses a method for synthesizing cisatracurium besilate. The method comprises the following steps of: reacting a compound shown as formula I, a compound shown as formula II and oxalicacid dihydrate to generate a compound shown as formula III; reacting the compound shown as formula III under the catalysis of Pd/C to generate a compound shown as formula IV; reacting the compound shown as formula IV with 1, 5-pentanediol to generate a compound shown as formula V; and reacting the compound shown as formula V with methyl benzenesulfonate to prepare cisatracurium besilate; whereinthe compounds shown as the formula I, the formula II, the formula III, the formula IV and the formula V are respectively represented as the specification. The synthesis method provided by the invention can significantly improve the yield and purity of cisatracurium besilate and reduce the synthesis cost of cisatracurium besilate.
Biodegradable neuromuscular blocking agents. Part 6. Stereochemical studies on atracurium and related polyalkylene di-esters
Stenlake,Waigh,Dewar,et al.
, p. 441 - 450 (2007/10/02)
Stereoisomers of atracurium (3, n=5) and one of its homologues each having the configuration, RR, SS and RS at the C(1)-positions have been synthesised. The ratio of cis and trans components in the RR-, SS- and RS/meso-products, which contain three, three
