64232-02-6Relevant academic research and scientific papers
REACTION OF ARYLIDENE-2-NAPHTHYLAMINES WITH THE ETHYL ESTER OF (2-QUINOLYL)-β-OXOPROPIONIC ACID
Gusak, K. N.,Serzhanina, V. A.,Kozlov, N. G.,Gren, V. V.
, p. 1220 - 1223 (1994)
The reaction of arylidene-2-naphthylamines with the ethyl ester of (2-quinolyl)-β-oxopropionic acid results in the synthesis of ethyl esters of 1-(2-quinolyl)-3-arylbenzoquinoline-2-carboxylic acids.All the theoretically possible intermediate reaction products were isolated: the amino esters of 2-quinoline-β-oxopropionic acid, the hydroxy esters of tetrahydro- and esters of dihydrobenzoquinoline-2-carboxylic acid, as well as the byproducts - the ethyl ester of 2-quinolyl-α-(R-benzylidene)-β-oxopropionic acid.The IR, UV, and mass spectra of the synthesized compounds are discussed.
β-oxoacids esters in the synthesis of benzo[f]quinoline derivatives
Gusak,Kozlov
, p. 706 - 718 (2008/02/08)
Condensation of ethyl acetoacetate and ethyl 3-oxo-3-(2-furyl-, 2-quinolyl-, 3-pyridyl)propanoates with azomethines of 2-naphthylamine series led to the formation of ethyl (3-arylbenzo[f]quinol-1-yl)acetates and of esters of the corresponding 3-aryl-1-heteryl-2-benzo[f]quinolylcarboxylic acids. The intermediate reaction products were isolated: ethyl 5-(2-naphthylamino)-3-oxo-5- phenylpentanoate, 2-[(aryl)(2-naphthylamino)methyl]-3-heteryl-3-oxopropanoates, dihydro and tetrahydro derivatives of benzoquinolylacetic and benzoquinolinecarboxylic acids. Nauka/Interperiodica 2007.
