75472-73-0

Usage

Uses

Used in Organic Synthesis:
(E)-N-(naphthalen-2-yl)-1-phenylmethanimine is used as a key intermediate in the synthesis of various organic molecules. Its unique structure allows for a wide range of chemical reactions, making it a versatile component in the development of new compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (E)-N-(naphthalen-2-yl)-1-phenylmethanimine is utilized as a building block for the development of new drugs. Its structural properties enable the creation of molecules with potential therapeutic applications, contributing to the advancement of medicinal chemistry.
Used in Materials Science:
(E)-N-(naphthalen-2-yl)-1-phenylmethanimine also has potential applications in the field of materials science. It can be employed in the creation of polymers and other advanced materials, where its structural characteristics may lead to the development of novel materials with unique properties.
Overall, (E)-N-(naphthalen-2-yl)-1-phenylmethanimine holds important implications in both academic research and industrial applications, making it a valuable compound in the realms of chemistry and materials science.

Upstream product

• 100-52-7 benzaldehyde 
• 91-59-8 naphthalen-2-ylamine 
• 100-51-6 benzyl alcohol 

Downstream Products

• 24896-64-8 4-phenyl-2,3-dihydro-1H-benzo[f]cyclopenta[c]quinoline 
• 306965-37-7 Ethyl 5-(2-naphthylamino)-3-oxo-5-phenylpentanoate 
• 306965-26-4 ethyl 2-(3-phenylbenzo[f]quinolin-1-yl)acetate 
• 41954-35-2 4-phenyl-2,3-dihydro-1H-benzo[f]cyclopenta[c]quinoline-1-carboxylic acid ethyl ester 
• 4067-82-7 1-methyl-3-phenyl-benzo[f]quinoline 
• 70311-09-0 ethyl 3-phenyl-1-(2-furyl)benzo[f]quinoline-2-carboxylate 
• 13672-18-9 benzyl-2-naphthylamine 

Relevant academic research and scientific papers

Cooperative catalysis of molybdenum with organocatalysts for distribution of products between amines and imines

Multi-amino groups and nitrogen donors compound was discovered as an organocatalyst for N-alkylation of alcohols with amines in the presence of Mo(CO)6. The Mo(CO)6/organocatalyst binary system has shown to be a highly active catalyst for the N-alkylation reaction between alcohols and amines with excellent tolerance of variable starting materials bearing different functional groups. Of particular note, this method possessing a superiority selectivity in the synthesis of N-alkylated amines or imines, which can be controlled by the reaction temperature. The cooperative catalysis mechanism in combination of Mo(CO)6 with organocatalyst was elucidated by control experiments.

A Highly Selective Manganese-Catalyzed Synthesis of Imines under Phosphine-Free Conditions

An efficient and highly selective phosphine-free NN-manganese(I) complex catalyst system was developed for the acceptorless dehydrogenative coupling of alcohols with amines to form imines. The coupling reactions underwent at 3 mol % catalyst loading, and a large range of alcohols and amines with diverse functional groups was applied, including challenging diol and diamine. The target imine products were obtained in good to excellent yields. The present work provides an alternative method to construct highly active nonprecious metal complex catalysts based on phosphine-free ligands.

Solvent-free synthesis of azomethines, spectral correlations and antimicrobial activities of some E-benzylidene-4-chlorobenzenamines

Some azomethines including substituted benzylidene-4-chlorobenzenamines (E-imines) have been synthesized by fly-ash: PTS catalyzed microwave assisted condensation of 4-chloroaniline and substituted benzaldehydes under solvent-free conditions. The yield of the imines has been found to be more than 85%. The purity of all imines has been checked using their physical constants and UV, IR and NMR spectral data. These spectral data have been correlated with Hammett substituent constants and F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the above spectral data has been studied. The antimicrobial activities of all imines have been studied using standard methods.

Condensation of laterally lithiated o-methyl and o-ethyl benzamides with imines mediated by (-)-sparteine. Enantioselective synthesis of tetrahydroisoquinolin-1-ones

The first asymmetric synthesis of tetrahydroisoquinolin-1-ones using a (-)-sparteine-mediated lateral metalation-imine addition sequence to furnish 3-phenyl tetrahydroisoquinolinones 3a with enantioselectivities up to 81% ee is described (Scheme 4). For amide 7b, imine addition products 10 and 11 have been obtained with high diastereoselectivities (91-97% de) and enantioselectivities (91-98% ee) (Scheme 8).

Condensation of ethyl cyclopentanone-2-carboxylate with N-arylmethylene-2-naphthylamines

The condensation of ethyl cyclopentanone-2-carboxylate with N-arylmethylene-2-naphthylamines depending on the conditions of reaction affords 4-aryl-1-ethoxycarbonyl-1H-2,3,4,5-tetrahydrocyclopenta[c]benzo[f]quinolines, 4-aryl-1-ethoxycarbonyl-1H-2,3-dihyd

Synthesis of 4-arylbenzo[f]cyclopenta[c]quinolines

The reaction of benzylidene-2-naphthylamine and its derivatives with cyclopentanone through intramolecylar heterocyclization in ～80% in one step yield afforded a number of previously unknown 4-arylbenzo[f]cyclopenta[c]quinolines.