6424-44-8Relevant articles and documents
Antihypercholesterolemic compounds and related pharmaceutical compositions and methods of use
-
, (2008/06/13)
Novel antihypercholesterolemic agents are provided. An exemplary group of compounds has the structural formula (I) STR1 wherein R is a C-17 side chain, R1 is --OH, =O, or the like, and X and Y are N, N→O, CH, C--OH, C--OCH3 or C--Z. Methods of using the compound of formula (I) or other novel oxysterol analogs to treat hypercholesterolemia are provided, as are pharmaceutical compositions containing the compounds.