6424-85-7

Basic information

• Product Name: ACID BLUE 40
• Synonyms: 10-dioxo-o-monosodiumsalt;2-anthracenedisulfonicacid,-[(4-(acetylamino)phenyl)amino]-1-amino-9,10-;2-Anthracenesulfonicacid,4-[[4-(acetylamino)phenyl]amino]-1-amino-9,10-dihydro-9,10-dioxo-,monosodiumsalt;acidblue40(c.i.62125);CI 62125;ACID BLUE 40;Acid Blue 40 (C.I.);C.I. Acid Blue 40
• CAS NO: 6424-85-7
• Molecular Formula: C₂₂H₁₆N₃O₆S*Na
• Molecular Weight: 473.43
• EINECS: 229-190-5
• Product Categories: Dyes and Pigments;A;Stains and Dyes;Stains&Dyes, A to
• Mol File: 6424-85-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: >300 °C
• Appearance: /
• CAS DataBase Reference: ACID BLUE 40(CAS DataBase Reference)
• NIST Chemistry Reference: ACID BLUE 40(6424-85-7)
• EPA Substance Registry System: ACID BLUE 40(6424-85-7)

Safety Data

• Hazardous Substances Data: 6424-85-7(Hazardous Substances Data)

Usage

Uses

Acid Blue 40 is an anthraquinone dye.

Preparation

1-Amino-4-bromo-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid and N-(4-aminophenyl)acetamide in copper salt and tied the presence of acid agents condensation, and then into sodium salt.

Properties and Applications

green light blue. Dark blue powder, soluble in water, solubility in water (80 ℃) 100 g/L, water solution is blue. Soluble in acetone and ethanol, slightly soluble in nitrobenzene, insoluble in benzene and dimethyl benzene, encounter the dark brown color of sulfuric acid, a product after diluted red; In the hydrochloric acid and sodium hydroxide solution discoloration. Mainly used for wool, polyamide fiber and silk dyeing and printing, also can be used for leather color. Standard Light Fastness Soaping Persperation Fastness Oxygen bleaching Fastness to seawater Fading Stain Fading Stain Fading Stain ISO 6 2 2 3 1-2 1-2 3 1-2 AATCC 5 1-2 1-2 2 1 1 2-3 2-3

Standard

Light Fastness

Fading

Stain

ISO

6

AATCC

5

InChI:InChI=1/C22H17N3O6S.Na/c1-11(26)24-12-6-8-13(9-7-12)25-16-10-17(32(29,30)31)20(23)19-18(16)21(27)14-4-2-3-5-15(14)22(19)28;/h2-10,25H,23H2,1H3,(H,24,26)(H,29,30,31);/q;+1/p-1

Upstream product

• 6258-06-6 sodium 1-amino-4-bromoanthraquinone-2-sulfonate 
• 122-80-5 N-acetyl-p-phenylenediamine 
• 116-81-4 1-amino-4-bromo-9,10-dioxoanthracene-2-sulphonic acid 

Downstream Products

• 753411-75-5 4-[4-(acetamino)phenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid 

Relevant articles and documents

High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors

Anthraquinone derivatives related to the moderately potent, nonselective P2Y12 receptor antagonist reactive blue 2 (6) have been synthesized and optimized with respect to P2Y12 receptor affinity. A radioligand binding assay utilizing human blood platelet membranes and the P2Y12 receptor-selective antagonist radioligand [3H]2-propylthioadenosine- 5′-adenylic acid (1,1-dichloro-1-phosphonomethyl-1-phosphonyl) anhydride ([3H]PSB-0413) was applied for compound testing. 1-Amino-2- sulfoanthraquinone derivatives bearing a (p-phenylamino) anilino substitution in the 4-position and an additional acidic function in the meta-position of the aniline ring showed high P2Y12 receptor affinity. These new anthraquinone derivatives became accessible by a recently developed copper(0)-catalyzed Ullmann coupling reaction of 1-amino-4-bromoanthraquinone derivatives with anilines in phosphate buffer under microwave irradiation. The most potent compounds exhibited Ki values of 24.9 nM (1-amino-4-[4-phenylamino-3-sulfophenylamino]-9,10-dioxo-9,10-dihydroanthracene- 2-sulfonate, PSB-0739, 39), and 21.0 nM (1-amino-4-[4-phenylamino-3- carboxyphenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate, PSB-0702, 41), respectively. 1-Amino-2-sulfo-4-anilinoanthraquinone derivatives appeared to be noncytotoxic, as shown for selected derivatives at two human cell lines (melanoma and astrocytoma). Compounds 39 and 41 represent new lead structures for the development of antithrombotic drugs.