6258-06-6

Basic information

• Product Name: 1-AMINO-4-BROMOANTHRAQUINONE-2-SULFONIC ACID SODIUM SALT
• Synonyms: 1-amino-4-bromanthrachinon-2-sulfonansodny;1-amino-4-bromo-9,10-dihydro-9,10-dioxo-2-anthracenesulfonicacimonosodi;1-amino-4-bromo-9,10-dihydro-9,10-dioxo-2-anthracenesulfonicacimonosodium;2-Anthracenesulfonicacid,1-amino-4-bromo-9,10-dihydro-9,10-dioxo-,monosodiumsalt;9,10-dihydro-1-amino-4-bromo-9,10-dioxo-2-anthracenesulfonicacisodiumsal;bromaminansodny;1-AMINO-4-BROMO-2-ANTHRAQUINONE-SULFONIC ACID SODIUM SALT;1-AMINO-4-BROMO-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENESULFONIC ACID, SODIUM SALT
• CAS NO: 6258-06-6
• Molecular Formula: C₁₄H₇BrNO₅S*Na
• Molecular Weight: 404.17
• EINECS: 228-391-5
• Product Categories: Anthraquinonesulfonic Acids;Aminoanthraquinones;Anthraquinones
• Mol File: 6258-06-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: >300 °C(lit.)
• Appearance: /
• CAS DataBase Reference: 1-AMINO-4-BROMOANTHRAQUINONE-2-SULFONIC ACID SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: 1-AMINO-4-BROMOANTHRAQUINONE-2-SULFONIC ACID SODIUM SALT(6258-06-6)
• EPA Substance Registry System: 1-AMINO-4-BROMOANTHRAQUINONE-2-SULFONIC ACID SODIUM SALT(6258-06-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 1
• RTECS: CB1090000
• Hazardous Substances Data: 6258-06-6(Hazardous Substances Data)

Usage

Uses

Bromaminic Acid Sodium Salt is the sodium salt of Bromaminic Acid (B679580). Bromaminic Acid Sodium Salt is used as a reactant in the preparation of aminoanthraquinone derivatives as potent and selective antagonists for the UTP-Activated P2Y4 Receptor. Dyes and metabolites.

InChI:InChI=1/C14H8BrNO5S.Na/c15-8-5-9(22(19,20)21)12(16)11-10(8)13(17)6-3-1-2-4-7(6)14(11)18;/h1-5H,16H2,(H,19,20,21);/q;+1/p-1

Upstream product

• 116-81-4 1-amino-4-bromo-9,10-dioxoanthracene-2-sulphonic acid 
• 24429-49-0 sodium 1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 82-45-1 1-amino-9,10-anthracenedione 
• 83-62-5 1-aminoanthraquinone-2-sulfonic acid 

Downstream Products

• 34940-32-4 Natrium-Salz von 1-Amino-4-methylamino-9,10-dioxo-9,10-dihydroanthracen-2-sulfonsaeure 
• 2786-71-2 1-amino-4-anilino-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid 
• 34824-60-7 Sodium; 1-amino-4-ethylamino-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonate 
• 24429-49-0 sodium 1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 25492-62-0 sodium 1-amino-4-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 6022-22-6 disodium 4,4'-diamino-1,1'-bianthraquinonyl-3,3'-disulfonate 
• 83-62-5 1-aminoanthraquinone-2-sulfonic acid 
• 4095-85-6 1,4-diamino-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid 
• 1052089-10-7 sodium 1-amino-4-(4-phenylthiophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 1052089-06-1 sodium 1-amino-4-(4-benzylphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 

Relevant articles and documents

Preparation process for sodium 1-amino-4-bromoanthraquinone-2-sulfonate

The invention discloses a preparation process for sodium 1-amino-4-bromoanthraquinone-2-sulfonate. The preparation process comprises the following steps: (1) sulfonation: with 1-aminoanthraquinone as a raw material, copper sulfate as a catalyst and dichloroethane as a solvent, carrying out dehydration, then adding chlorosulfonic acid drop by drop for a sulfonation reaction, adding 98% concentrated sulfuric acid after completion of the reaction, extracting 1-aminoanthraquinone-2-sulfonic acid out, allowing 1-aminoanthraquinone-2-sulfonic acid to enter the concentrated sulfuric acid, separating out an acid phase at a lower layer and subjecting the acid phase to a subsequent reaction; (2) bromination: adding bromine into the concentrated sulfuric acid solution of 1-aminoanthraquinone-2-sulfonic acid drop by drop for a reaction so as to obtain the concentrated sulfuric acid solution of bromoamine acid; (3) dilution: adding water into the concentrated sulfuric acid solution of bromoamine acid for dilution and successively carrying out cooling, crystallization and filtering so as to obtain bromoamine acid; and (4) salt formation: adding water to dissolve bromoamine acid and adding sodium sulfite to obtain bromoamine acid sodium salt. The preparation process provided by the invention can reduce energy consumption during solvent recovery; the utilization rate of bromine in bromination is high; sodium sulfite is used for salt formation, so the amount of impurities is reduced; and product quality is high.

OPTIMIZATION OF THE OXIDATIVE BROMINATION OF 1-AMINOANTHRAQUINONE-2-SULFONIC ACID

An efficient method of synthesis of 1-amino-4-bromoanthraquinone-2-sulfonic acid using bromination of the corresponding aminoathraquinonesulfonic acid with bromine in the presence of hydrogen peroxide has been proposed.The optimum conditions of synthesis, with a yield of the target product of 68percent, have been found.