6258-06-6

Basic information

• Product Name: 1-AMINO-4-BROMOANTHRAQUINONE-2-SULFONIC ACID SODIUM SALT
• Synonyms: 1-amino-4-bromanthrachinon-2-sulfonansodny;1-amino-4-bromo-9,10-dihydro-9,10-dioxo-2-anthracenesulfonicacimonosodi;1-amino-4-bromo-9,10-dihydro-9,10-dioxo-2-anthracenesulfonicacimonosodium;2-Anthracenesulfonicacid,1-amino-4-bromo-9,10-dihydro-9,10-dioxo-,monosodiumsalt;9,10-dihydro-1-amino-4-bromo-9,10-dioxo-2-anthracenesulfonicacisodiumsal;bromaminansodny;1-AMINO-4-BROMO-2-ANTHRAQUINONE-SULFONIC ACID SODIUM SALT;1-AMINO-4-BROMO-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENESULFONIC ACID, SODIUM SALT
• CAS NO: 6258-06-6
• Molecular Formula: C₁₄H₇BrNO₅S*Na
• Molecular Weight: 404.17
• EINECS: 228-391-5
• Product Categories: Anthraquinonesulfonic Acids;Aminoanthraquinones;Anthraquinones
• Mol File: 6258-06-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: >300 °C(lit.)
• Appearance: /
• CAS DataBase Reference: 1-AMINO-4-BROMOANTHRAQUINONE-2-SULFONIC ACID SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: 1-AMINO-4-BROMOANTHRAQUINONE-2-SULFONIC ACID SODIUM SALT(6258-06-6)
• EPA Substance Registry System: 1-AMINO-4-BROMOANTHRAQUINONE-2-SULFONIC ACID SODIUM SALT(6258-06-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 1
• RTECS: CB1090000
• Hazardous Substances Data: 6258-06-6(Hazardous Substances Data)

Usage

Description

1-AMINO-4-BROMOANTHRAQUINONE-2-SULFONIC ACID SODIUM SALT, also known as Bromaminic Acid Sodium Salt, is a chemical compound derived from the sodium salt of Bromaminic Acid (B679580). It is characterized by its unique molecular structure, which contributes to its diverse applications in various industries.

Uses

Used in Pharmaceutical Industry:
1-AMINO-4-BROMOANTHRAQUINONE-2-SULFONIC ACID SODIUM SALT is used as a reactant for the preparation of aminoanthraquinone derivatives. These derivatives are potent and selective antagonists for the UTP-Activated P2Y4 Receptor, which play a crucial role in various physiological processes and therapeutic applications.
Used in Dye Industry:
1-AMINO-4-BROMOANTHRAQUINONE-2-SULFONIC ACID SODIUM SALT is utilized as a key component in the synthesis of dyes. Its unique chemical properties enable the creation of dyes with specific characteristics, making it a valuable asset in the development of new and improved dye formulations.
Used in Metabolite Research:
In the field of metabolite research, 1-AMINO-4-BROMOANTHRAQUINONE-2-SULFONIC ACID SODIUM SALT serves as a vital compound for studying the metabolic pathways and interactions of various biological systems. Its role in this area is essential for understanding the complex processes that occur within living organisms and can contribute to the development of new therapeutic strategies and diagnostic tools.

InChI:InChI=1/C14H8BrNO5S.Na/c15-8-5-9(22(19,20)21)12(16)11-10(8)13(17)6-3-1-2-4-7(6)14(11)18;/h1-5H,16H2,(H,19,20,21);/q;+1/p-1

Upstream product

• 116-81-4 1-amino-4-bromo-9,10-dioxoanthracene-2-sulphonic acid 
• 24429-49-0 sodium 1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 82-45-1 1-amino-9,10-anthracenedione 
• 83-62-5 1-aminoanthraquinone-2-sulfonic acid 

Downstream Products

• 20349-48-8 disodium 1-amino-4-(4-amino-2-sulfophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 15827-21-1 disodium 1-amino-4-(4-amino-3-sulfophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 1213268-67-7 sodium 1-amino-4-(4-phenoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 78510-32-4 sodium 1-amino-4-(4-bromophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 40951-76-6 sodium 1-amino-4-((4-aminophenyl)amino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 1052089-14-1 sodium 1-amino-4-(benzylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 1213268-70-2 sodium 1-amino-4-(4-bromo-2-carboxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 1213268-65-5 sodium 1-amino-4-(4-chlorophenethylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 18837-50-8 sodium 1-amino-4-(2-phenethylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 1052089-12-9 C₂₄H₂₁N₂O₇S^(1-)*Na⁽¹⁺⁾ 
• 4368-56-3 Natrium-Salz von 1-Amino-4-cyclohexylamino-9,10-dioxo-9,10-dihydroanthracen-2-sulfonsaeure 
• 50314-37-9 sodium 1-amino-4-(4-hydroxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 
• 116679-68-6 C₂₀H₁₄N₃O₈S₂^(1-)*Na⁽¹⁺⁾ 
• 1213268-68-8 sodium 1-amino-4-[4-(diethoxyphosphoryl)methylphenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate 

Relevant articles and documents

Preparation process for sodium 1-amino-4-bromoanthraquinone-2-sulfonate

The invention discloses a preparation process for sodium 1-amino-4-bromoanthraquinone-2-sulfonate. The preparation process comprises the following steps: (1) sulfonation: with 1-aminoanthraquinone as a raw material, copper sulfate as a catalyst and dichloroethane as a solvent, carrying out dehydration, then adding chlorosulfonic acid drop by drop for a sulfonation reaction, adding 98% concentrated sulfuric acid after completion of the reaction, extracting 1-aminoanthraquinone-2-sulfonic acid out, allowing 1-aminoanthraquinone-2-sulfonic acid to enter the concentrated sulfuric acid, separating out an acid phase at a lower layer and subjecting the acid phase to a subsequent reaction; (2) bromination: adding bromine into the concentrated sulfuric acid solution of 1-aminoanthraquinone-2-sulfonic acid drop by drop for a reaction so as to obtain the concentrated sulfuric acid solution of bromoamine acid; (3) dilution: adding water into the concentrated sulfuric acid solution of bromoamine acid for dilution and successively carrying out cooling, crystallization and filtering so as to obtain bromoamine acid; and (4) salt formation: adding water to dissolve bromoamine acid and adding sodium sulfite to obtain bromoamine acid sodium salt. The preparation process provided by the invention can reduce energy consumption during solvent recovery; the utilization rate of bromine in bromination is high; sodium sulfite is used for salt formation, so the amount of impurities is reduced; and product quality is high.

OPTIMIZATION OF THE OXIDATIVE BROMINATION OF 1-AMINOANTHRAQUINONE-2-SULFONIC ACID

An efficient method of synthesis of 1-amino-4-bromoanthraquinone-2-sulfonic acid using bromination of the corresponding aminoathraquinonesulfonic acid with bromine in the presence of hydrogen peroxide has been proposed.The optimum conditions of synthesis, with a yield of the target product of 68percent, have been found.