64240-81-9

Upstream product

• 89-78-1 menthol 
• 2216-51-5 (-)-menthol 
• 5989-49-1 di-p-menthan-3-yl-diazene-N-oxide 
• 10034-85-2 hydrogen iodide 
• 89-78-1 (-)-menthol 
• 134052-28-1 2-((1S,2R,5S)-2-Isopropyl-5-methyl-cyclohexyloxy)-tetrahydro-pyran 
• 15356-70-4 menthol 
• 89-48-5 2-isopropyl-5-methylcyclohexyl acetate 

Downstream Products

• 500-00-5 3-p-menthene 
• 619-52-3 (1R)-menth-3-ene 
• 99-82-1 Menthane 

Relevant academic research and scientific papers

4-Aminophenyldiphenylphosphinite (APDPP), a new heterogeneous and acid scavenger phosphinite - Conversion of alcohols, trimethylsilyl, and tetrahydropyranyl ethers to alkyl halides with halogens or N-halosuccinimides

A new heterogeneous phosphinite, 4-aminophenyldiphenylphosphinite (APDPP), is prepared and used for the efficient conversion of alcohols, trimethylsilyl ethers, and tetrahydropyranyl ethers to their corresponding bromides, iodides, and chlorides in the presence of molecular halogens or N-halosuccinimides. The amino group in this phosphinite acts as an acid scavenger and removes the produced acid. A simple filtration easily removes the phosphinate by-product.

A facile conversion of tetrahydropyranyl ethers to the corresponding bromides and iodides

Tetrahydropyranyl ethers are converted to the corresponding bromides and iodides upon reaction with NaI (or Libr) and BF3.Et2O (or ClSiMe3).

Facile Conversion of Primary and Secondary Alcohols to Alkyl Iodides

A convenient, simple procedure is described for the conversion of a variety of primary and secondary alcohols to iodides in yields ranging from 60-98percent.The method employs the Ph3P/imidazole/I2 combination of reagents in the solvent dichloromethane.